Health benefits of astaxanthin against age-related diseases of multiple organs: A comprehensive review

P Alugoju, VKD Krishna Swamy… - Critical Reviews in …, 2023 - Taylor & Francis
Age-related diseases are associated with increased morbidity in the past few decades and
the cost associated with the treatment of these age-related diseases exerts a substantial …

Astaxanthin as a modulator of Nrf2, NF-κB, and their crosstalk: molecular mechanisms and possible clinical applications

S Davinelli, L Saso, F D'Angeli, V Calabrese, M Intrieri… - Molecules, 2022 - mdpi.com
Astaxanthin (AST) is a dietary xanthophyll predominantly found in marine organisms and
seafood. Due to its unique molecular features, AST has an excellent antioxidant activity with …

Geniposide alleviates diabetic nephropathy of mice through AMPK/SIRT1/NF-κB pathway

F Li, Y Chen, Y Li, M Huang, W Zhao - European Journal of Pharmacology, 2020 - Elsevier
Geniposide (GE) can effectively inhibit diabetic nephropathy (DN), but its mechanism is
unclear. The objective of this study was to explore the antidiabetic nephropathy effects of GE …

Protective effect of astaxanthin on ochratoxin A-induced kidney injury to mice by regulating oxidative stress-related NRF2/KEAP1 pathway

L Li, Y Chen, D Jiao, S Yang, L Li, P Li - Molecules, 2020 - mdpi.com
The present study aimed to investigate the effects of astaxanthin (ASX) on ochratoxin A
(OTA)-induced renal oxidative stress and its mechanism of action. Serum kidney markers …

Ameliorative impacts of astaxanthin against atrazine-induced renal toxicity through the modulation of ionic homeostasis and Nrf2 signaling pathways in mice

MM Soliman, KS Alotaibi, SB Albattal… - Toxicology …, 2024 - academic.oup.com
Astaxanthin (ASX), a red pigment belonging to carotenoids, has antioxidant activity and anti-
oxidative stress effect. Atrazine (ATZ), a frequently used herbicide, whose degradation …

Natural astaxanthin enhanced antioxidant capacity and improved semen quality through the MAPK/Nrf2 pathway in aging layer breeder roosters

S Gao, N Heng, F Liu, Y Guo, Y Chen, L Wang… - Journal of Animal …, 2021 - Springer
Background Natural astaxanthin (ASTA) has strong antioxidant properties and has been
widely used as a health product to improve human health. However, the effects of ASTA on …

Astaxanthin improves lipotoxicity, lipid peroxidation and oxidative stress in kidney of sucrose-rich diet-fed rats

MBV Joubert, PI Ingaramo, P Collins… - The Journal of …, 2025 - Elsevier
Metabolic Syndrome (MS) is a cluster of metabolic risk factors, characterized by abdominal
obesity, dyslipidemia, hypertension, insulin resistance, among others. The purpose of the …

Research on the effects of L-carnitine and trans-chalcone on endoplasmic reticulum stress and oxidative stress in high-fructose corn syrup-fed rats

V Unsal, K Deveci, ZC Ozmen, MK Tumer - Nutrition & Food Science, 2021 - emerald.com
Purpose The debate on the metabolic effects of high fructose corn syrup (HFCS) continues.
The deterioration of endoplasmic reticulum (ER) homeostasis is called ER stress. Glucose …

Effect of genipin-1-β-d-gentiobioside on diabetic nephropathy in mice by activating AMP-activated protein kinase/silencing information regulator-related enzyme 1 …

F Li, L Song, J Chen, Y Chen, Y Li… - Journal of Pharmacy …, 2021 - academic.oup.com
Abstract Objectives Genipin-1-β-d-gentiobioside (GG) is a kind of compound extracted from
Gardenia jasminoides Ellis. The chemical structure of GG is similar to that of geniposide and …

Natural Astaxanthin Improves Testosterone Synthesis and Sperm Mitochondrial Function in Aging Roosters

S Gao, BX Zhao, C Long, N Heng, Y Guo, XH Sheng… - Antioxidants, 2022 - mdpi.com
Spermatogenesis, sperm motility, and apoptosis are dependent on the regulation of
glandular hormones and mitochondria. Natural astaxanthin (ASTA) has antioxidant, anti …