Association of SGLT2 inhibitors with cardiovascular, kidney, and safety outcomes among patients with diabetic kidney disease: a meta-analysis

AD Kaze, M Zhuo, SC Kim, E Patorno… - Cardiovascular diabetology, 2022 - Springer
Background We conducted a systematic review and meta-analysis of the cardiovascular,
kidney, and safety outcomes of sodium-glucose cotransporter 2 inhibitors (SGLT2i) among …

Efficacy and safety profile of SGLT2 inhibitors in the elderly: How is the benefit/risk balance?

AJ Scheen, F Bonnet - Diabetes & Metabolism, 2023 - Elsevier
Type 2 diabetes mellitus (T2DM) is a highly prevalent health condition in the aging
population. Older adults with T2DM have higher risks of cardiovascular disease, heart failure …

Comparing effectiveness and safety of SGLT2 inhibitors vs DPP-4 inhibitors in patients with type 2 diabetes and varying baseline HbA1c levels

E D'Andrea, DJ Wexler, SC Kim, JM Paik… - JAMA internal …, 2023 - jamanetwork.com
Importance Sodium-glucose cotransporter 2 inhibitor (SGLT2i) therapy has been associated
with cardiovascular benefits and a few adverse events; however, whether the comparative …

SGLT2-inhibitors are effective and safe in the elderly: The SOLD study

ME Lunati, V Cimino, A Gandolfi, M Trevisan… - Pharmacological …, 2022 - Elsevier
Background and aims Sodium-glucose co-transporter-2 inhibitors (SGLT2i) may have
important benefits for the elderly with type 2 diabetes (T2D), however some safety concerns …

[HTML][HTML] Acute kidney injury in diabetes mellitus: epidemiology, diagnostic and therapeutic concepts

Y Gui, Z Palanza, H Fu, D Zhou - FASEB journal: official publication …, 2023 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) and diabetes mellitus (DM) are public health problems that cause a
high socioeconomic burden worldwide. In recent years, the landscape of AKI etiology has …

Association of sodium–glucose cotransporter 2 inhibitors with time to dementia: a population-based cohort study

CY Wu, C Iskander, C Wang, LY Xiong… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE Type 2 diabetes (T2D) increases dementia risk, but clear evidence to
recommend interventions that can mitigate that risk remains lacking. This population-based …

Sodium-glucose transport protein 2 inhibitor use for type 2 diabetes and the incidence of acute kidney injury in Taiwan

MC Chung, PH Hung, PJ Hsiao, LY Wu… - JAMA Network …, 2023 - jamanetwork.com
Importance The association between sodium-glucose transport protein 2 inhibitor (SGLT2i)
use and the incidence of acute kidney injury (AKI) remains controversial. The benefits of …

Safety of sodium‐glucose cotransporter 2 inhibitors in elderly patients with type 2 diabetes: A meta‐analysis of randomized controlled trials

M Rigato, GP Fadini, A Avogaro - Diabetes, Obesity and …, 2023 - Wiley Online Library
Aim Sodium‐glucose cotransporter 2 inhibitors (SGLT2is) are particularly effective in
preventing adverse outcomes of heart failure and chronic kidney disease, which are highly …

Sodium glucose co-transporter-2 inhibitors in intensive care unit patients with type 2 diabetes: a pilot case control study

J Mårtensson, SL Cutuli, EA Osawa, F Yanase, L Toh… - Critical Care, 2023 - Springer
Background Sodium glucose co-transporter-2 (SGLT2) inhibitors improve long-term
cardiovascular and renal outcomes in individuals with type 2 diabetes. However, the safety …

Contrast-induced acute kidney injury in patients on SGLT2 inhibitors undergoing percutaneous coronary interventions: a propensity-matched analysis

R Hua, N Ding, H Guo, Y Wu, Z Yuan… - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Background Contrast-induced acute kidney injury (CI-AKI) is a common complication of
patients undergoing percutaneous coronary intervention (PCI). Data regarding the influence …