Opportunities and challenges in the therapeutic exploitation of histamine and histamine receptor pharmacology in inflammation-driven disorders
Inflammation-driven diseases encompass a wide array of pathological conditions
characterised by immune system dysregulation leading to tissue damage and dysfunction …
characterised by immune system dysregulation leading to tissue damage and dysfunction …
Fexofenadine-loaded chitosan coated solid lipid nanoparticles (SLNs): A potential oral therapy for ulcerative colitis
The targeting and mucoadhesive features of chitosan (CS)-linked solid lipid nanoparticles
(SLNs) were exploited to efficiently deliver fexofenadine (FEX) into the colon, forming a …
(SLNs) were exploited to efficiently deliver fexofenadine (FEX) into the colon, forming a …
Drug Repurposing in Crohn's Disease Using Danish Real-World Data
S Shakibfar, KH Allin, T Jess, MA Barbieri… - Pragmatic and …, 2024 - Taylor & Francis
Aim Drug repurposing, utilizing electronic healthcare records (EHRs), offers a promising
alternative by repurposing existing drugs for new therapeutic indications, especially for …
alternative by repurposing existing drugs for new therapeutic indications, especially for …
Integration of National Health Insurance claims data and animal models reveals fexofenadine as a promising repurposed drug for Parkinson's disease
Background Parkinson's disease (PD) is a common and costly progressive
neurodegenerative disease of unclear etiology. A disease-modifying approach that can …
neurodegenerative disease of unclear etiology. A disease-modifying approach that can …
[HTML][HTML] Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice
Obesity has a multifactorial etiology and is known to be a state of chronic low-grade
inflammation, known as meta-inflammation. This state is associated with the development of …
inflammation, known as meta-inflammation. This state is associated with the development of …
Effects of osthole on inflammatory gene expression and cytokine secretion in histamine-induced inflammation in the caco-2 cell line
NK Kordulewska, J Topa, D Rozmus… - International Journal of …, 2021 - mdpi.com
Hyperactivity of the immune system in the gastrointestinal tract leads to the development of
chronic, inflammation-associated disorders. Such diseases, including inflammatory bowel …
chronic, inflammation-associated disorders. Such diseases, including inflammatory bowel …
Topical formulations and compositions
M Kandula - US Patent 11,833,141, 2023 - Google Patents
US11833141B2 - Topical formulations and compositions - Google Patents US11833141B2 -
Topical formulations and compositions - Google Patents Topical formulations and compositions …
Topical formulations and compositions - Google Patents Topical formulations and compositions …