Natural polymer-based antimicrobial hydrogels without synthetic antibiotics as wound dressings

Y Zhong, H Xiao, F Seidi, Y Jin - Biomacromolecules, 2020 - ACS Publications
Wound healing is usually accompanied by bacterial infection. The excessive use of synthetic
antibiotics leads to drug resistance, posing a significant threat to human health. Hydrogel …

Methicillin-resistant Staphylococcus aureus (MRSA): antibiotic-resistance and the biofilm phenotype

KM Craft, JM Nguyen, LJ Berg, SD Townsend - MedChemComm, 2019 - pubs.rsc.org
Staphylococcus aureus (S. aureus) is an asymptomatic colonizer of 30% of all human
beings. While generally benign, antibiotic resistance contributes to the success of S. aureus …

Biodegradable and cytocompatible hydrogel coating with antibacterial activity for the prevention of implant-associated infection

Y Liu, T Dong, Y Chen, N Sun, Q Liu… - … Applied Materials & …, 2023 - ACS Publications
Implant-associated infection (IAI) caused by pathogens colonizing on the implant surface is
a serious issue in the trauma-orthopedic surgery, which often leads to implant failure. The …

Alternatives to conventional antibiotics in the era of antimicrobial resistance

C Ghosh, P Sarkar, R Issa, J Haldar - Trends in microbiology, 2019 - cell.com
As more antibiotics are rendered ineffective by drug-resistant bacteria, focus must be shifted
towards alternative therapies for treating infections. Although several alternatives already …

Antibacterial quaternary ammonium agents: Chemical diversity and biological mechanism

W Dan, J Gao, X Qi, J Wang, J Dai - European journal of medicinal …, 2022 - Elsevier
Bacterial infections have seriously threatened public health especially with the increasing
resistance and the cliff-like decline of the number of newly approved antibacterial agents …

Recent progress in polymer research to tackle infections and antimicrobial resistance

MM Konai, B Bhattacharjee, S Ghosh… - …, 2018 - ACS Publications
Global health is increasingly being threatened by the rapid emergence of drug-resistant
microbes. The ability of these microbes to form biofilms has further exacerbated the scenario …

Recent developments in smart antibacterial surfaces to inhibit biofilm formation and bacterial infections

X Li, B Wu, H Chen, K Nan, Y Jin, L Sun… - Journal of materials …, 2018 - pubs.rsc.org
Since their development over 70 years, antibiotics are still the most effective strategy to treat
bacterial biofilms and infections. However, the overuse of antibiotics in human healthcare …

Functional hydrogels for diabetic wound management

D Gao, Y Zhang, DT Bowers, W Liu, M Ma - APL bioengineering, 2021 - pubs.aip.org
Diabetic wounds often have a slow healing process and become easily infected owing to
hyperglycemia in wound beds. Once planktonic bacterial cells develop into biofilms, the …

Biocompatible injectable hydrogel with potent wound healing and antibacterial properties

J Hoque, RG Prakash, K Paramanandham… - Molecular …, 2017 - ACS Publications
Two component injectable hydrogels that cross-link in situ have been used as noninvasive
wound-filling devices, ie, sealants. These materials carry a variety of functions at the wound …

Polymeric biomaterials for prevention and therapeutic intervention of microbial infections

S Ghosh, S Mukherjee, D Patra, J Haldar - Biomacromolecules, 2022 - ACS Publications
The escalating emergence of multidrug-resistant (MDR) pathogens and their ability to
colonize into biofilms on a multitude of surfaces have struck global health as a nightmare …