Mycobacterium tuberculosis (Mtb) is one of the most important infectious agents worldwide
and causes more than 1.5 million deaths annually. To make matters worse, the drug …

The ribonuclease A superfamily is a vertebrate-specific family of proteins that encompasses
eight functional members in humans. The proteins are secreted by diverse innate immune …

Respiratory infections remain a major global health concern. Tuberculosis is one of the top
10 causes of death worldwide, while infections with Non‐Tuberculous Mycobacteria are …

Innate immunity of the mucosal surfaces provides the first-line defense from invading
pathogens and pollutants conferring protection from the external environment. Innate …

Smoking increases susceptibility to becoming infected with and developing tuberculosis.
Among the components of cigarette smoke, nicotine has been identified as the main …

The human ribonuclease RNase 7 has been originally isolated from human skin and is a
member of the human RNase A superfamily. RNase 7 is constantly released by …

The development of novel treatment against tuberculosis is a priority global health
challenge. Antimicrobial proteins and peptides offer a multifaceted mechanism suitable to …

Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is second only to COVID-19 as
the top infectious disease killer worldwide. Multi-drug resistant TB (MDR-TB) may arise …

Antibiotic resistance is an increasing global problem and therapeutic alternatives to
traditional antibiotics are needed. Antimicrobial and host defense peptides represent an …

Background Diabetic foot ulcers (DFUs) are one of the main complications in patients with
type 2 diabetes mellitus (DM2), previous studies have reported that DM2 patients have lower …