Implementation of clinical practice guidelines (CPG) is a complex and challenging task.
Computer technology, including artificial intelligence (AI), has been explored to promote the …

Background The over-use of antibiotics in clinical domains is causing an alarming increase
in bacterial resistance, thus endangering their effectiveness as regards the treatment of …

This third and final installment of this series on innovative designs for the smart ICU
addresses the steps involved in conceptualizing, actualizing, using, and maintaining the …

Abstract The Intensive Care Unit is a data intensive environment where large volumes of
patient monitoring and observational data are daily generated. Today, there is a lack of an …

A standards-based, service-oriented architecture for clinical decision support (CDS) has the
potential to significantly enhance CDS scalability and robustness. To enable such a CDS …

Abstract The Arden Syntax is an HL7 standard language for representing medical
knowledge as logic statements. Despite nearly 2 decades of availability, Arden Syntax has …

Considerable research has recently focused on integrating cyber-physical systems in a
social context. However, several challenges remain concerning appropriate methodologies …

Abstract The Clinical Decision Support Consortium has completed two demonstration trials
involving a web service for the execution of clinical decision support (CDS) rules in one or …

Since there is a great confusion between the ontologies and other semantic resources, the
purpose of this special issue is to address the question on “Ontologies and terminologies …

Advanced informatics systems can help improve health care delivery and the environment of
care for critically ill patients. However, identifying, testing, and deploying advanced …