Exosomes are tiny membrane-bound vesicles that are over produced by most proliferating
cell types during normal and pathological states. Their levels are up-regulated during …

Venous and arterial thromboses, called as cancer-associated thromboembolism (CAT), are
common complications in cancer patients that are associated with high mortality. The cell …

Background Tisotumab vedotin is a first-in-human antibody–drug conjugate directed against
tissue factor, which is expressed across multiple solid tumour types and is associated with …

Ovarian clear cell carcinoma can arise from endometriosis; however, it is distinct from other
types of epithelial ovarian carcinoma in terms of its clinicopathological and molecular …

Pancreatic cancer frequently involves cancer‐associated thromboembolism, which is
strongly associated with poor prognosis. Tissue factor, a blood coagulation factor largely …

Ovarian cancer is the most lethal gynecological malignancy, which is due to late
presentation. Treating advanced stage ovarian cancer is difficult, and tumor recurrence and …

A State-of-the-Art lecture titled “Mechanisms of cancer-associated thrombosis” was
presented at the ISTH Congress in 2022. Patients with cancer have a 4-fold to 9-fold …

In the last decade, antibody-drug conjugates (ADCs), normally formed by a humanized
antibody and a small drug via a chemical cleavable or non-cleavable linker, have emerged …

Aim Postoperative pulmonary embolism can be a fatal surgical complication and is thought
to occur secondary to asymptomatic venous thromboembolism (VTE) that exists …

This review focuses on the immunosuppressive effects of tumor angiogenesis and
coagulation on the tumor microenvironment (TME). We summarize previous research efforts …