Introduction A systematic literature review was undertaken to evaluate real-world use of
ceftazidime-avibactam for infections due to aerobic Gram-negative organisms in adults with …

Intra-abdominal infections (IAI) are among the most common global healthcare challenges
and they are usually precipitated by disruption to the gastrointestinal (GI) tract. Their …

Extended spectrum β-lactamase (ESBL)-producing bacteria are prevalent worldwide and
correlated with hospital infections, but they have been evolving as an increasing cause of …

The rising incidence of bloodstream infections (BSI) due to Gram-negative bacteria (GNB)
with difficult-to-treat resistance (DTR) has been recognized as a global emergency. The aim …

Abstract Ceftolozane-tazobactam (C/T), ceftazidime-avibactam (C/A), and meropenem/
vaborbactam (M/V) are new beta-lactam/beta-lactamase combination antibiotics commonly …

ABSTRACT Ceftolozane/tazobactam (C/T) is a novel β-lactam/β-lactamase inhibitor
combination targeting Enterobacteriaceae and Pseudomonas aeruginosa (PA). It is …

New therapeutic agents against ESBL-and AmpC-producing Enterobacterales have
distinctive specificities and limitations that require further investigations. Future randomized …

Background Carbapenem-sparing antibiotics are needed urgently for patients with
complicated intra-abdominal infections (cIAIs). Although several novel antibiotics–novel β …

Abstract Background The global Study of Monitoring Antimicrobial Resistance Trends
(SMART) is a surveillance program for evaluation of antimicrobial resistance (AMR) in Gram …

Treatment of extended-spectrum β-lactamases infections: what... : Current Opinion in
Infectious Diseases Treatment of extended-spectrum β-lactamases infections: what is the …