Phage adsorption to gram-positive bacteria

A Leprince, J Mahillon - Viruses, 2023 - mdpi.com
The phage life cycle is a multi-stage process initiated by the recognition and attachment of
the virus to its bacterial host. This adsorption step depends on the specific interaction …

Bacteriophages in the dairy industry: a problem solved?

G Ortiz Charneco, PP de Waal… - Annual Review of …, 2023 - annualreviews.org
Bacteriophages (or phages) represent one of the most persistent threats to food
fermentations, particularly large-scale commercial dairy fermentations. Phages infecting …

The atomic structure of the phage Tuc2009 baseplate tripod suggests that host recognition involves two different carbohydrate binding modules

P Legrand, B Collins, S Blangy, J Murphy, S Spinelli… - MBio, 2016 - Am Soc Microbiol
ABSTRACT The Gram-positive bacterium Lactococcus lactis, used for the production of
cheeses and other fermented dairy products, falls victim frequently to fortuitous infection by …

Host recognition by lactic acid bacterial phages

J Mahony, C Cambillau… - FEMS Microbiology …, 2017 - academic.oup.com
Bacteriophage infection of lactic acid bacteria (LAB) is one of the most significant causes of
inconsistencies in the manufacture of fermented foods, affecting production schedules and …

Structure of the host-recognition device of Staphylococcus aureus phage ϕ11

C Koç, G Xia, P Kühner, S Spinelli, A Roussel… - Scientific reports, 2016 - nature.com
Phages play key roles in the pathogenicity and adaptation of the human pathogen
Staphylococcus aureus. However, little is known about the molecular recognition events that …

Functional carbohydrate binding modules identified in evolved dits from siphophages infecting various Gram‐positive bacteria

S Hayes, R Vincentelli, J Mahony, A Nauta… - Molecular …, 2018 - Wiley Online Library
With increasing numbers of 3D structures of bacteriophage components, combined with
powerful in silico predictive tools, it has become possible to decipher the structural assembly …

Phage-host interactions of cheese-making lactic acid bacteria

J Mahony, B McDonnell, E Casey… - Annual review of food …, 2016 - annualreviews.org
Cheese production is a global biotechnological practice that is reliant on robust and
technologically appropriate starter and adjunct starter cultures to acidify the milk and impart …

Structural studies of the rhamnose-rich cell wall polysaccharide of Lactobacillus casei BL23

E Vinogradov, I Sadovskaya, T Grard… - Carbohydrate …, 2016 - Elsevier
Lactobacillus casei is a Gram positive lactic acid bacterium used in dairy fermentations and
present in the normal human gut microbiota. Certain strains are recognized as probiotics …

Evolved distal tail carbohydrate binding modules of Lactobacillus phage J‐1: a novel type of anti‐receptor widespread among lactic acid bacteria phages

ME Dieterle, S Spinelli, I Sadovskaya… - Molecular …, 2017 - Wiley Online Library
Bacteriophage replication requires specific host‐recognition. Some siphophages harbour a
large complex, the baseplate, at the tip of their non‐contractile tail. This baseplate holds …

Genetic and functional characterisation of the lactococcal P335 phage-host interactions

J Mahony, J Oliveira, B Collins, L Hanemaaijer… - BMC genomics, 2017 - Springer
Background Despite continuous research efforts, bacterio (phages) infecting Lactococcus
lactis starter strains persist as a major threat to dairy fermentations. The lactococcal P335 …