Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape

NI Mazur, J Terstappen, R Baral, A Bardají… - The Lancet Infectious …, 2023 - thelancet.com
Respiratory syncytial virus is the second most common cause of infant mortality and a major
cause of morbidity and mortality in older adults (aged> 60 years). Efforts to develop a …

Development of mRNA vaccines against respiratory syncytial virus (RSV)

X Qiu, S Xu, Y Lu, Z Luo, Y Yan, C Wang, J Ji - Cytokine & Growth Factor …, 2022 - Elsevier
Respiratory syncytial virus (RSV) is a single-stranded negative-sense RNA virus that is the
primary etiologic pathogen of bronchitis and pneumonia in infants and the elderly. Currently …

[HTML][HTML] New viral vectors for infectious diseases and cancer

E Sasso, AM D'Alise, N Zambrano, E Scarselli… - Seminars in …, 2020 - Elsevier
Since the discovery in 1796 by Edward Jenner of vaccinia virus as a way to prevent and
finally eradicate smallpox, the concept of using a virus to fight another virus has evolved into …

[HTML][HTML] Respiratory syncytial virus: from pathogenesis to potential therapeutic strategies

Z Shang, S Tan, D Ma - International Journal of Biological Sciences, 2021 - ncbi.nlm.nih.gov
Respiratory syncytial virus (RSV) is one of the most important viral pathogens causing
respiratory tract infection in infants, the elderly and people with poor immune function, which …

[HTML][HTML] Adenovirus-based vaccines—a platform for pandemic preparedness against emerging viral pathogens

L Coughlan, EJ Kremer, DM Shayakhmetov - Molecular Therapy, 2022 - cell.com
Zoonotic viruses continually pose a pandemic threat. Infection of humans with viruses for
which we typically have little or no prior immunity can result in epidemics with high morbidity …

The immunogenicity and safety of respiratory syncytial virus vaccines in development: A systematic review

J Shan, PN Britton, CL King… - Influenza and other …, 2021 - Wiley Online Library
Background Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory
infection globally. There are vaccine candidates in development, but a systematic review on …

Current state and challenges in developing respiratory syncytial virus vaccines

C Biagi, A Dondi, S Scarpini, A Rocca, S Vandini… - Vaccines, 2020 - mdpi.com
Respiratory syncytial virus (RSV) is the main cause of acute respiratory tract infections in
infants and it also induces significant disease in the elderly. The clinical course may be …

Respiratory syncytial virus infection in the modern era

M Ludlow - Current opinion in infectious diseases, 2023 - journals.lww.com
Respiratory syncytial virus infection in the modern era : Current Opinion in Infectious
Diseases Respiratory syncytial virus infection in the modern era : Current Opinion in …

Phase 1/2a safety and immunogenicity of an adenovirus 26 vector respiratory syncytial virus (RSV) vaccine encoding prefusion F in adults 18–50 years and RSV …

ASV Stuart, M Virta, K Williams, I Seppa… - The Journal of …, 2023 - academic.oup.com
Background Respiratory syncytial virus (RSV) remains a leading cause of pediatric
morbidity, with no approved vaccine. We assessed the safety and immunogenicity of the …

Aging and options to halt declining immunity to virus infections

MÁ Palacios-Pedrero, ADME Osterhaus… - Frontiers in …, 2021 - frontiersin.org
Immunosenescence is a process associated with aging that leads to dysregulation of cells of
innate and adaptive immunity, which may become dysfunctional. Consequently, older adults …