[HTML][HTML] Review of in vitro mechanical testing for intervertebral disc injectable biomaterials

AR Dixon, JP Warren, MP Culbert, M Mengoni… - Journal of the …, 2021 - Elsevier
Many early stage interventions for intervertebral disc degeneration are under development
involving injection of a biomaterial into the affected tissue. Due to the complex mechanical …

[HTML][HTML] Customized composite intervertebral disc scaffolds by integrated 3D bioprinting for therapeutic implantation

D Wu, J Tan, L Yao, J Tian, B Luo, L Li, C Zhou… - Composites Part A …, 2021 - Elsevier
In the past few years, tissue-engineered total disc replacement (TE-TDR) as a possible
strategy to repair or regenerate intervertebral disc (IVD) has attracted considerable attention …

Experimental and computational comparison of intervertebral disc bulge for specimen-specific model evaluation based on imaging

M Mengoni, FY Zapata-Cornelio… - … in Bioengineering and …, 2021 - frontiersin.org
Finite element modelling of the spinal unit is a promising preclinical tool to assess the
biomechanical outcome of emerging interventions. Currently, most models are calibrated …

A Modified finite element model of a poroviscoelastic intervertebral disc

SF Veisari, M Haghpanahi, H Saberi - … : Applications, Basis and …, 2022 - World Scientific
The intervertebral disc (IVD) is the soft tissue between the vertebral bodies, which is
responsible for transmitting multi-directional loads through the spine and to allow relative …

Injectable peptide-glycosaminoglycan hydrogels for soft tissue repair: in vitro assessment for nucleus augmentation

JP Warren, RH Coe, MP Culbert, AR Dixon… - Materials …, 2024 - pubs.rsc.org
We report the development of peptide-glycosaminoglycan hydrogels as injectable
biomaterials for load-bearing soft tissue repair. The hydrogels are injectable as a liquid for …

Clinically quantifiable measures from an in vitro study of nucleus augmentation of the intervertebral disc

A Dixon, J Warren, M Culbert, A Khan, M Mengoni… - 2023 - engrxiv.org
Purpose: Nucleus augmentation has been proposed as an early-stage intervention for
intervertebral disc degeneration and involves the injection of a biomaterial into the nucleus …