Incubating green synthesized iron oxide nanorods for proteomics-derived motif exploration: A fusion to deep learning oncogenesis
Y Manzoor, M Hasan, A Zafar, M Dilshad… - ACS …, 2022 - ACS Publications
The nanotechnological arena has revolutionized the diagnostic efficacies by investigating
the protein corona. This displays provoking proficiencies in determining biomarkers and …
the protein corona. This displays provoking proficiencies in determining biomarkers and …
Pharmacogenomics of Drugs Used in β-Thalassemia and Sickle-Cell Disease: From Basic Research to Clinical Applications
In this short review we have presented and discussed studies on pharmacogenomics (also
termed pharmacogenetics) of the drugs employed in the treatment of β-thalassemia or Sickle …
termed pharmacogenetics) of the drugs employed in the treatment of β-thalassemia or Sickle …
Activating transcription factor 4 in erythroid development and -thalassemia: a powerful regulator with therapeutic potential
J Li, A Lv, M Chen, L Xu, H Huang - Annals of hematology, 2024 - Springer
Abstract Activating transcription factor 4 (ATF4) is a fundamental basic region/leucine zipper
transcription factor, responds to various stress signals, and plays crucial roles in normal …
transcription factor, responds to various stress signals, and plays crucial roles in normal …
Human cellular model systems of β-thalassemia enable in-depth analysis of disease phenotype
DE Daniels, I Ferrer-Vicens, J Hawksworth… - Nature …, 2023 - nature.com
Abstract β-thalassemia is a prevalent genetic disorder causing severe anemia due to
defective erythropoiesis, with few treatment options. Studying the underlying molecular …
defective erythropoiesis, with few treatment options. Studying the underlying molecular …
Prime Editor 3 Mediated Beta-Thalassemia Mutations of the HBB Gene in Human Erythroid Progenitor Cells
H Zhang, Q Zhou, H Chen, D Lu - International Journal of Molecular …, 2022 - mdpi.com
Recently developed Prime Editor 3 (PE3) has been implemented to induce genome editing
in various cell types but has not been proven in human hematopoietic stem and progenitor …
in various cell types but has not been proven in human hematopoietic stem and progenitor …
[HTML][HTML] Erythropoiesis and Gene Expression Analysis in Erythroid Progenitor Cells Derived from Patients with Hemoglobin H/Constant Spring Disease
N Wongkhammul, P Khamphikham, S Tongjai… - International Journal of …, 2024 - mdpi.com
Hemoglobin H/Constant Spring (Hb H/CS) disease represents a form of non-deletional Hb H
disease characterized by chronic hemolytic anemia that ranges from moderate to severe …
disease characterized by chronic hemolytic anemia that ranges from moderate to severe …
A Review of CRISPR Cas9 for SCA: Treatment Strategies and Could Target β-globin Gene and BCL11A Gene using CRISPR Cas9 Prevent the Patient from Sickle …
BACKGROUND: Sickle cell anemia is a hereditary globin chain condition that leads to
hemolysis and persistent organ damage. Chronic hemolytic anemia, severe acute and …
hemolysis and persistent organ damage. Chronic hemolytic anemia, severe acute and …
[PDF][PDF] Choirotussanijjah. A Review of CRISPR Cas9 for SCA: Treatment Strategies and Could Target β-globin Gene and BCL11A Gene using CRISPR Cas9 Prevent …
BE Suwito, AS Adji, JS Widjaja, SCS Angel… - 2023 - researchgate.net
BACKGROUND: Sickle cell anemia is a hereditary globin chain condition that leads to
hemolysis and persistent organ damage. Chronic hemolytic anemia, severe acute and …
hemolysis and persistent organ damage. Chronic hemolytic anemia, severe acute and …
Tissue-specific variations in transcription factors elucidate complex immune system regulation
H Lu, YC Tang, A Gottlieb - Genes, 2022 - mdpi.com
Gene expression plays a key role in health and disease. Estimating the genetic components
underlying gene expression can thus help understand disease etiology. Polygenic models …
underlying gene expression can thus help understand disease etiology. Polygenic models …
Ferroptosis, un mecanismo de muerte celular presente en β-talasemia menor
MM Terán, ME Mónaco, C Haro… - Revista Bioquímica y …, 2025 - revistabypc.org.ar
La ferroptosis es un tipo de muerte celular programada, dependiente de hierro, impulsada
por una severa peroxidación lipídica, la cual es consecuencia del metabolismo celular y de …
por una severa peroxidación lipídica, la cual es consecuencia del metabolismo celular y de …