[HTML][HTML] Retinal pigment epithelium 65 kDa protein (RPE65): An update
PD Kiser - Progress in retinal and eye research, 2022 - Elsevier
Vertebrate vision critically depends on an 11-cis-retinoid renewal system known as the
visual cycle. At the heart of this metabolic pathway is an enzyme known as retinal pigment …
visual cycle. At the heart of this metabolic pathway is an enzyme known as retinal pigment …
RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy
Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB
PDB, rcsb. org), the US data center for the global PDB archive, serves thousands of Data …
PDB, rcsb. org), the US data center for the global PDB archive, serves thousands of Data …
USP18–a multifunctional component in the interferon response
Ubiquitin-specific proteases (USPs) represent the largest family of deubiquitinating enzymes
(DUB). These proteases cleave the isopeptide bond between ubiquitin and a lysine residue …
(DUB). These proteases cleave the isopeptide bond between ubiquitin and a lysine residue …
Blind prediction of homo‐and hetero‐protein complexes: The CASP13‐CAPRI experiment
MF Lensink, G Brysbaert, N Nadzirin… - Proteins: Structure …, 2019 - Wiley Online Library
We present the results for CAPRI Round 46, the third joint CASP‐CAPRI protein assembly
prediction challenge. The Round comprised a total of 20 targets including 14 homo …
prediction challenge. The Round comprised a total of 20 targets including 14 homo …
Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders
Hypusination is a unique post-translational modification of the eukaryotic translation factor
5A (eIF5A) that is essential for overcoming ribosome stalling at polyproline sequence …
5A (eIF5A) that is essential for overcoming ribosome stalling at polyproline sequence …
GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway
V Kroef, S Ruegenberg, M Horn, K Allmeroth, L Ebert… - Elife, 2022 - elifesciences.org
The hexosamine biosynthetic pathway (HBP) produces the essential metabolite UDP-
GlcNAc and plays a key role in metabolism, health, and aging. The HBP is controlled by its …
GlcNAc and plays a key role in metabolism, health, and aging. The HBP is controlled by its …
Assessment of the CASP14 assembly predictions
B Ozden, A Kryshtafovych… - … : Structure, Function, and …, 2021 - Wiley Online Library
In CASP14, 39 research groups submitted more than 2500 3D models on 22 protein
complexes. In general, the community performed well in predicting the fold of the assemblies …
complexes. In general, the community performed well in predicting the fold of the assemblies …
A complete rule set for designing symmetry combination materials from protein molecules
Diverse efforts in protein engineering are beginning to produce novel kinds of symmetric self-
assembling architectures, from protein cages to extended two-dimensional (2D) and three …
assembling architectures, from protein cages to extended two-dimensional (2D) and three …
PPI3D: a web server for searching, analyzing and modeling protein–protein, protein–peptide and protein–nucleic acid interactions
Abstract Structure-resolved protein interactions with other proteins, peptides and nucleic
acids are key for understanding molecular mechanisms. The PPI3D web server enables …
acids are key for understanding molecular mechanisms. The PPI3D web server enables …
Structural dynamics in the evolution of a bilobed protein scaffold
G Gouridis, YA Muthahari, M de Boer… - Proceedings of the …, 2021 - National Acad Sciences
Novel biophysical tools allow the structural dynamics of proteins and the regulation of such
dynamics by binding partners to be explored in unprecedented detail. Although this has …
dynamics by binding partners to be explored in unprecedented detail. Although this has …