Liver regeneration after hepatectomy and partial liver transplantation

S Yagi, M Hirata, Y Miyachi, S Uemoto - International Journal of …, 2020 - mdpi.com
The liver is a unique organ with an abundant regenerative capacity. Therefore, partial
hepatectomy (PHx) or partial liver transplantation (PLTx) can be safely performed. Liver …

Effect of immunosuppressive agents on hepatocyte apoptosis post-liver transplantation

EJ Lim, R Chin, U Nachbur, J Silke, Z Jia, PW Angus… - Plos one, 2015 - journals.plos.org
Introduction Immunosuppressants are used ubiquitously post-liver transplantation to prevent
allograft rejection. However their effects on hepatocytes are unknown. Experimental data …

Effects of selective bile duct ligation on liver parenchyma in young animals: histologic and molecular evaluations

ACA Tannuri, MCM Coelho… - Journal of Pediatric …, 2012 - Elsevier
BACKGROUND/PURPOSE: The mechanisms of increased collagen production and liver
parenchyma fibrosis are poorly understood. These phenomena are observed mainly in …

Attenuation of warm ischemia–reperfusion injury in the liver by bucillamine through decreased neutrophil activation and Bax/Bcl‐2 modulation

SP Junnarkar, N Tapuria, A Mani, S Dijk… - Journal of …, 2010 - Wiley Online Library
Abstract Background and Aim: Liver transplantation and resection surgery involve a period
of ischemia and reperfusion to the liver, which initiates an inflammatory cascade resulting in …

Effect of leflunomide on liver regeneration after partial hepatectomy in rats

A Karaman, H Kirimlioglu, E Tas, N Karadag… - Pediatric surgery …, 2010 - Springer
Purpose Partial hepatectomy (PH) can be an inevitable surgical therapy in some conditions,
such as hepatic malignancies, trauma or partial liver transplantation. Its capacity for …

Effects of tacrolimus and insulin in a liver regeneration model in growing animals with portal vein stenosis: immunohistochemical and molecular studies

AN Backes, ACA Tannuri, FN Backes… - Pediatric surgery …, 2014 - Springer
The aim of the present investigation was to describe a new model of liver regeneration in
growing rats with reduced portal flow. In addition, it was studied whether tacrolimus and …

Does Arterialization of Portal Vein Have Any Effects in Large-for-Size Liver Transplantation? Hemodynamic, Histological, and Biomolecular Experimental Studies

RR Torres, ACA Tannuri, S Serafini… - Journal of …, 2022 - Taylor & Francis
Background: In pediatric liver transplantation, the optimal size of the transplanted liver
ranges between 0.8% and 4.0% of the recipient's weight. Sometimes, the graft weight …

The nude mouse as model for liver deficiency study and treatment and xenotransplantation

I Vidal, L Richert - International journal of hepatology, 2012 - Wiley Online Library
We aimed at reviewing the various uses of Nude mouse for the development of liver
deficiency models and evaluation of efficacy of hepatic cell xenotransplantation. The first …

[HTML][HTML] Immunohistochemical study of the ameliorative effect of vitamin e on liver regeneration after different periods of partial hepatectomy

MM Halawani, GSA Aziz, HA Amin… - Biomedical and …, 2018 - biomedpharmajournal.org
The liver is almost unique in its capacity for regeneration after hepatectomy but the exact
mechanisms are not yet fully clarified. Antioxidants have been shown to promote liver …

Caspase 信号通路调控大鼠再生肝肝细胞的凋亡

蒋文文, 郝晓霞, 郭雅琼, 赵卫明, 徐存拴 - 解剖学报, 2012 - jpxb.bjmu.edu.cn
Objective To explore the role of Caspase signaling pathway in regulating hepatocytes of the
rat regenerating liver. Methods A total of 114 adult rats were randomly divided into 19 …