Cancer stem cells and cancer therapy

S Soltanian, MM Matin - Tumor Biology, 2011 - Springer
Cancer stem cells (CSCs) are a subpopulation of tumour cells that possess the stem cell
properties of self-renewal and differentiation. Stem cells might be the target cells responsible …

[HTML][HTML] Cytotoxic activity of the genus Ferula (Apiaceae) and its bioactive constituents

M Iranshahi, R Rezaee, MN Najafi… - Avicenna Journal of …, 2018 - ncbi.nlm.nih.gov
Objective: The genus Ferula L. includes perennial flowering plants belonging to the
Apiaceae family. This genus is a rich source of biologically active phytochemicals such as …

Sesquiterpene Coumarin Ethers with Selective Cytotoxic Activities from the Roots of Ferula huber-morathii Peşmen (Apiaceae) and Unequivocal Determination of the …

FM Eruçar, FK Kuran, G Altıparmak Ülbegi, S Özbey… - Pharmaceuticals, 2023 - mdpi.com
Ancient physicians frequently used the resin of Ferula species to treat cancer. Today, some
folkloric recipes used for cancer treatment also contain the resin of Ferula species. The …

Potent anti-angiogenic and cytotoxic effect of conferone on human colorectal adenocarcinoma HT-29 cells

O Cheraghi, G Dehghan, M Mahdavi, R Rahbarghazi… - Phytomedicine, 2016 - Elsevier
Background Cancer is one of the leading causes of death worldwide, both in developed and
developing countries. Of note, colorectal adenoma encompasses a high rate of …

Coumarins as potential anti-drug resistant cancer agents: A mini review

G Wang, S Sun, B Wu, J Liu - Current topics in medicinal …, 2021 - ingentaconnect.com
Cancer is the main cause of death, and the emergence of resistance by cancer cells towards
existing anticancer agents is one of the major problems for effective chemotherapy, creating …

Ferutinin, an apoptosis inducing terpenoid from Ferula ovina

MM Matin, H Nakhaeizadeh, AR Bahrami… - Asian Pacific Journal …, 2014 - koreascience.kr
A current hurdle in cancer management is the intrinsic or acquired resistance of cancer cells
to chemical agents that restricts the efficacy of therapeutic strategies. Accordingly, there is an …

Investigating anticancer properties of the sesquiterpene ferutinin on colon carcinoma cells, in vitro and in vivo

N Arghiani, MM Matin, AR Bahrami, M Iranshahi… - Life sciences, 2014 - Elsevier
Aims In this research, ferutinin was evaluated for its possible cytotoxic and apoptotic
inducing effects in vitro and in vivo. Main methods To determine IC 50 values of ferutinin …

Scolicidal effectiveness of essential oil from Zataria multiflora and Ferula assafoetida: disparity between phenolic monoterpenes and disulphide compounds

G Kavoosi, AM Purfard - Comparative Clinical Pathology, 2013 - Springer
Hydatidosis in humans and animals is a substantial cause of deaths in many parts of the
world. Surgery and the chemotherapeutic agents are the main treatments for hydatid …

Investigating the cytotoxic and apoptosis inducing effects of monoterpenoid stylosin in vitro

FB Rassouli, MM Matin, M Iranshahi, AR Bahrami - Fitoterapia, 2011 - Elsevier
The aim of this study was to investigate the cytotoxic and anticancer activities of stylosin, a
monoterpene extracted from an edible plant, Ferula ovina, on 5637 and HFF3 cells using …

Cytotoxic and apoptotic effects of Ferula gummosa Boiss: extract on human breast adenocarcinoma cell line

R Rashidi, A Roohbakhsh, L Mohtashami… - Molecular Biology …, 2024 - Springer
Abstract Purpose Ferula gummosa Boiss. is a well-known and valuable medicinal plant in
Iran. Research has shown that this plant has several pharmacological properties, including …