Small animal radiotherapy research platforms

F Verhaegen, P Granton… - Physics in Medicine & …, 2011 - iopscience.iop.org
Advances in conformal radiation therapy and advancements in pre-clinical radiotherapy
research have recently stimulated the development of precise micro-irradiators for small …

Dosimetry: Was and Is an Absolute Requirement for Quality Radiation Research

D Johnson, HH Li, BF Kimler - Radiation Research, 2024 - meridian.allenpress.com
This review aims to trace the evolution of dosimetry, highlight its significance in the
advancement of radiation research, and identify the current trends and methodologies in the …

Molecularly targeted gold nanoparticles enhance the radiation response of breast cancer cells and tumor xenografts to X-radiation

N Chattopadhyay, Z Cai, YL Kwon, E Lechtman… - Breast cancer research …, 2013 - Springer
The purpose of this study was to evaluate the effect of molecularly targeted gold
nanoparticles (AuNPs) on tumor radiosensitization both in vitro and in vivo. Human …

The importance of tissue segmentation for dose calculations for kilovoltage radiation therapy

M Bazalova, EE Graves - Medical physics, 2011 - Wiley Online Library
Purpose: The aim of this work was to evaluate the effect of tissue segmentation on the
accuracy of Monte Carlo (MC) dose calculations for kilovoltage radiation therapy, which are …

[HTML][HTML] Radiation dose enhancement in skin therapy with nanoparticle addition: A Monte Carlo study on kilovoltage photon and megavoltage electron beams

XJ Zheng, JCL Chow - World Journal of Radiology, 2017 - ncbi.nlm.nih.gov
AIM To investigated the dose enhancement due to the incorporation of nanoparticles in skin
therapy using the kilovoltage (kV) photon and megavoltage (MV) electron beams. Monte …

Construction of mouse phantoms from segmented CT scan data for radiation dosimetry studies

D Welch, AD Harken… - Physics in Medicine & …, 2015 - iopscience.iop.org
We present the complete construction methodology for an anatomically accurate mouse
phantom made using materials which mimic the characteristics of tissue, lung, and bone for …

Investigation of the effects of cell model and subcellular location of gold nanoparticles on nuclear dose enhancement factors using Monte Carlo simulation

Z Cai, JP Pignol, N Chattopadhyay, YL Kwon… - Medical …, 2013 - Wiley Online Library
Purpose: The authors' aims were to model how various factors influence radiation dose
enhancement by gold nanoparticles (AuNPs) and to propose a new modeling approach to …

Development of computational small animal models and their applications in preclinical imaging and therapy research

T Xie, H Zaidi - Medical physics, 2016 - Wiley Online Library
The development of multimodality preclinical imaging techniques and the rapid growth of
realistic computer simulation tools have promoted the construction and application of …

The impact of dual energy CT imaging on dose calculations for pre-clinical studies

A Vaniqui, LEJR Schyns, IP Almeida… - Radiation …, 2017 - Springer
Background To investigate the feasibility of using dual-energy CT (DECT) for tissue
segmentation and kilovolt (kV) dose calculations in pre-clinical studies and assess potential …

Fast dynamic electron paramagnetic resonance (EPR) oxygen imaging using low-rank tensors

AG Christodoulou, G Redler, B Clifford, ZP Liang… - Journal of magnetic …, 2016 - Elsevier
Hypoxic tumors are resistant to radiotherapy, motivating the development of tools to image
local oxygen concentrations. It is generally believed that stable or chronic hypoxia is the …