Wet granulation is a very important unit operation that finds applications in many industries
mainly pharmaceutical and chemical industries. Various granulation technologies in batch …

High shear wet granulation (HSWG) is considered a complicated and multivariate
pharmaceutical process that is influenced by a large number of variables derived from …

As a consequence of increasing computer power and more readily useable commercial and
open source codes, Discrete Element Method (DEM) is becoming widely used across a …

The development of scientifically based fibrous porous networks has been gaining
momentum due to their potential advantages in a wide spectrum of end-uses. Flow of fluid …

Numerical analysis via the DEM has been applied to various powder processes. To obtain
simulation results of high reliability, a calibration method for the input DEM parameters must …

The use of Discrete Element Method (DEM) modelling is rapidly expanding as a modelling
tool to analyse particulate processes and to address technological needs in various aspects …

Numerical simulation of wet granulation in a continuous granulator is carried out using
Discrete Element Method (DEM) to discover the possibility of formation of seeded granules …

Wet granulation is a complex particle design process often operated inefficiently in industrial
applications. Enhanced process understanding is required to facilitate design, control, and …

Granulation plays an important role in various manufacturing sectors, including the
chemical, pharmaceutical, and agricultural sectors. Computer simulation by coupling a …

The effective implementation of Quality by Design (QbD) for wet granulation requires
quantitative models for design and scaling of granulators. This paper reviews that current …