[HTML][HTML] Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy

I Riquelme, K Saavedra, JA Espinoza, H Weber… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Gastric cancer (GC) is the third leading cause of cancer mortality worldwide. Although
surgical resection is a potentially curative approach for localized cases of GC, most cases of …

Alternative splicing regulation of telomerase: a new paradigm?

MS Wong, WE Wright, JW Shay - Trends in genetics, 2014 - cell.com
Alternative splicing affects approximately 95% of eukaryotic genes, greatly expanding the
coding capacity of complex genomes. Although our understanding of alternative splicing has …

A performance evaluation of drug response prediction models for individual drugs

A Park, Y Lee, S Nam - Scientific Reports, 2023 - nature.com
Drug response prediction is important to establish personalized medicine for cancer therapy.
Model construction for predicting drug response (ie, cell viability half-maximal inhibitory …

CtBP promotes metastasis of breast cancer through repressing cholesterol and activating TGF-β signaling

Z Zhao, D Hao, L Wang, J Li, Y Meng, P Li, Y Wang… - Oncogene, 2019 - nature.com
Metastasis is the process through which the primary cancer cells spread beyond the primary
tumor and disseminate to other organs. Most cancer patients die of metastatic disease. EMT …

[HTML][HTML] Inflammatory microenvironment contributes to epithelial-mesenchymal transition in gastric cancer

HY Ma, XZ Liu, CM Liang - World journal of gastroenterology, 2016 - ncbi.nlm.nih.gov
Gastric cancer (GC) is the fifth most common malignancy in the world. The major cause of
GC is chronic infection with Helicobacter pylori (H. pylori). Infection with H. pylori leads to an …

Comprehensive analysis of the expression and prognosis for laminin genes in ovarian cancer

P Yang, B Diao - Pathology and Oncology Research, 2021 - por-journal.com
Survival is low in ovarian cancer (OC). Most OC patients demonstrate advanced metastases,
and recurrence is common. Dysregulation of laminin interactions is associated with cancer …

Laminins and cancer stem cells: Partners in crime?

Y Qin, S Rodin, OE Simonson, F Hollande - Seminars in cancer biology, 2017 - Elsevier
As one of the predominant protein families within the extracellular matrix both structurally
and functionally, laminins have been shown to be heavily involved in tumor progression and …

[PDF][PDF] RETRACTED: Knockdown of Long Non-Coding RNA KCNQ1OT1 Restrained Glioma Cells' Malignancy by Activating miR-370/CCNE2 Axis

W Gong, J Zheng, X Liu, Y Liu, J Guo, Y Gao… - Frontiers in cellular …, 2017 - frontiersin.org
Accumulating evidence has highlighted the potential role of long non-coding RNAs
(lncRNAs) as biomarkers and therapeutic targets in solid tumors. Here, we elucidated the …

Demethoxycurcumin: A naturally occurring curcumin analogue with antitumor properties

M Hatamipour, M Ramezani… - Journal of Cellular …, 2018 - Wiley Online Library
The eradication of cancer in a patient remains an elusive challenge despite advances in
early detection and diagnosis, chemo‐and immunotherapy, pinpoint radiation treatments …

Laminin gene LAMB4 is somatically mutated and expressionally altered in gastric and colorectal cancers

MR Choi, CH An, NJ Yoo, SH Lee - Apmis, 2015 - Wiley Online Library
Laminins are important in tumor invasion and metastasis as well as in maintenance of
normal epithelial cell structures. However, mutation status of laminin chain‐encoding genes …