Maintenance of Na+ and K+ gradients across the cell plasma membrane is an essential
process for mammalian cell survival. An enzyme responsible for this process, sodium …

The signaling function of the Na/K-ATPase has been established for 20 years and is widely
accepted in the field, with many excellent reports and reviews not cited here. Even though …

Muscle weakness associated with sarcopenia is a major contributor to reduced health span
and quality of life in the elderly. However, the underlying mechanisms of muscle weakness …

Aging has been associated with a series of pathophysiological processes causing general
decline in the overall health of the afflicted population. The cumulative line of evidence …

The slow accumulation of inflammatory biomarker levels in the body—also known as
inflammaging—has been linked to a myriad of age-related diseases. Some of these include …

Abstract Non-Alcoholic Fatty Liver Disease (NAFLD) has been recognized as the most
common liver disorder in developed countries. NAFLD progresses from fat accumulation in …

Development of metal-free, recyclable enzyme mimics is challenging and requires key
chemical modifications at the molecular level. Here, nitrilotriacetic acid-functionalized …

In 1972 Neal Bricker presented the “trade-off” hypothesis in which he detailed the role of
physiological adaptation processes in mediating some of the pathophysiology associated …

Aim Highly prevalent diseases such as insulin resistance and heart failure are characterized
by reduced metabolic flexibility and reserve. We tested whether Na/K‐ATPase (NKA) …

(1) Background: Nonalcoholic fatty liver disease (NAFLD) is primarily characterized by the
presence of fatty liver, hepatic inflammation and fibrogenesis eventually leading to …