Abstract Purpose of the Review High-density lipoproteins (HDL) are responsible for the
transport in plasma of a large fraction of circulating lipids, in part from tissue mobilization …

The systemic RNAi-defective (SID) transmembrane family member 2 (SIDT2) is a putative
nucleic acid channel or transporter that plays essential roles in nucleic acid transport and …

Chronic liver disease is a global health issue. Patients with chronic liver disease require a
fresh approach that focuses on the genetic and environmental factors that contribute to …

In Mendelian randomization, two single SNP-trait correlation-based methods have been
developed to infer the causal direction between an exposure (eg, a gene) and an outcome …

Abstract Background and Aim Non‐alcoholic fatty liver disease (NAFLD) is the most
common cause of liver disease. Increasing evidence indicates that the gut microbiota can …

Hepatic de novo lipogenesis is influenced by the branched-chain α-keto acid
dehydrogenase (BCKDH) kinase (BCKDK). Here, we aimed to determine whether …

SIDT2 is a lysosomal protein involved in the degradation of nucleic acids and the transport
of cholesterol between membranes. Previous studies identified two “cholesterol …

Susceptibility to metabolic syndrome (MetS) is dependent on genetics, environment, and
gene-by-environment interactions, rendering the study of underlying mechanisms …

The ancient city of Chichén Itzá in Yucatán, Mexico, was one of the largest and most
influential Maya settlements during the Late and Terminal Classic periods (ad 600–1000) …

Previous studies have reported that the SIDT2 and ABCA1 genes are involved in lipid
metabolism. We aimed to analyze the association—the gene x gene interaction between …