Infection is the likeliest single cause of delayed healing in healing of chronic open wounds
by secondary intention. If neglected it can progress from contamination to colonization and …

Highlights•Superbugs such as MRSA are highly prevalent infections with high mortality
rates.•Biofilms and antibiotic resistance impede effective treatment of MRSA.•Conventional …

Antibiotic‐loaded bone cement (ALBC) is broadly used to treat orthopaedic infections based
on the rationale that high‐dose local delivery is essential to eradicate biofilm‐associated …

Background Foot infections are a major cause of morbidity in people with diabetes and the
most common cause of diabetes-related hospitalization and lower extremity amputation …

Abstract Background Biodegradable chitosan nanoparticles (CSNPs) with an intrinsic
antimicrobial activity may be a good choice to improve the effectiveness of antimicrobial …

Escherichia coli is the most common cause of Gram-negative prosthetic joint infections
(PJIs) and ciprofloxacin is the first-line antibiofilm antibiotic. Due to the emergence of …

While microbial biofilms have been recognized as being ubiquitous in nature for the past 40
years, it has only been within the past 20 years that clinical practitioners have realized that …

Multidrug-resistant (MDR) Enterococcus faecium is a challenging nosocomial pathogen
known to colonize medical device surfaces and form biofilms. Bacterio (phages) may …

Campylobacter and Salmonella are leading causes of foodborne illnesses worldwide, vastly
harboured by raw meat as their common food reservoir. Both microbes are prevalent in meat …

Background: Methicillin-resistant Staphylococcus aureus bacteremia (MRSA-B) may fail to
improve with standard monotherapy, particularly in patients with multifocal infection …