Spinal cord injuries (SCIs) are associated with tremendous physical, social, and financial
costs for millions of individuals and families worldwide. Rapid delivery of specialized …

Osteoporosis is a systemic disease that affects the skeleton, causing reduction of bone
density and mass, resulting in destruction of bone microstructure and increased risk of bone …

This note reports observations of the change of stiffness of human mesenchymal stem cells
(hMSCs) with the progress of cell death as measured by AFM. hMSC with impaired …

Decentralized or “redistributed” manufacturing has the potential to revolutionize the
manufacturing approach for cell and gene therapies (CGTs), moving away from the “Fordist” …

Background The cell and gene therapy (CGT) field is at a critical juncture. Clinical successes
have underpinned the requirement for developing manufacturing capacity suited to patient …

Successful preliminary studies have encouraged a more translational phase for stem cell
research. Nevertheless, advances in the culture of human bone marrow-derived …

The low cell engraftment after transplantation limits the successful application of stem cell
therapy and the exact pathway leading to acute donor cell death following transplantation is …

The cell therapy industry is rapidly growing with several new products approved for clinical
use over the past few years and many more currently in clinical trials. Nonetheless, a …

Encouraging advances in cell therapies have produced a requirement for an effective short-
term cell preservation method, enabling time for quality assurance testing and transport to …

Equine mesenchymal stromal cells (MSC) are commonly transported, chilled or frozen, to
veterinary clinics. These MSC must remain viable and minimally affected by culture …