Iron is an essential trace element for the human body, and its deficiency or excess can
induce a variety of biological processes. Plenty of evidences have shown that iron …

One of the long-standing goals of both researchers and oncologists is to establish a
framework for the complete cure of cancer with less toxic adverse effect and improved …

Metal nanoparticles used as antifungals have increased the occurrence of fungal–metal
interactions. However, there is a lack of knowledge about how these interactions cause …

The circadian clock temporally coordinates metabolic homeostasis in mammals. Central to
this is heme, an iron-containing porphyrin that serves as prosthetic group for enzymes …

Albumin is a constitutional plasma protein, with well-known biological functions, eg, a
nutrient for stem cells in culture. However, albumin is underutilized as a biomaterial in …

Protoporphyrin IX iron complex (heme) is an important cofactor for oxygen transfer, oxygen
storage, oxygen activation, and electron transfer when bound to the heme proteins …

The role of phosphoglycerate dehydrogenase (PHGDH), a key enzyme of the serine
synthesis pathway (SSP), in endothelial cells (ECs) remains poorly characterized. We report …

Heme is a ubiquitous and essential iron containing metallo-organic cofactor required for
virtually all aerobic life. Heme synthesis is initiated and completed in mitochondria, followed …

The appearance of heme, an organic ring surrounding an iron atom, in evolution forever
changed the efficiency with which organisms were able to generate energy, utilize gasses …

An iron-containing, tetrapyrrole ring, heme is an essential prosthetic group in an array of
proteins that comprehensively affect cellular function and metabolism; yet “free” heme in …