Diabetic retinopathy is a neurovascular complication of diabetes and the main cause of
vision loss in adults. Glial cells have a key role in maintenance of central nervous system …

Neuropathic Pain (NPP) is caused by direct or indirect damage to the nervous system and is
a common symptom of many diseases. Clinically, drugs are usually used to suppress pain …

The limited access to functional human brain tissue has led to the development of stem cell-
based alternative models. The differentiation of human pluripotent stem cells into cerebral …

The occurrence and development of tumors is a multi-factor, multi-step, multi-gene
pathological process, and its treatment has been the most difficult problem in the field of …

Pancreatic stellate cells (PSCs) are important pancreatic fibrogenic cells that interact with
pancreatic cancer cells to promote the progression of pancreatic ductal adenocarcinoma …

Background and Purpose Regulating macrophage–hepatocyte crosstalk through P2X7
receptors has led to new pharmacological strategies to reverse alcoholic hepatosteatosis …

In avascular wound repair, calcium signaling events are the predominant mechanism cells
use to transduce information about stressors in the environment into an effective and …

The retina is the sensory tissue responsible for the first stages of visual processing, with a
conserved anatomy and functional architecture among vertebrates. To date, retinal eye …

Neuroglia interactions are essential for the nervous system and in the retina Müller cells
interact with most of the neurons in a symbiotic manner. Glutathione (GSH) is a low …

Abstract P2X7 receptor (P2X7R) is an ATP-gated non-selective cation channel which
mediates ATP-induced inflammation in macrophages. Transient receptor potential (TRP) …