Protein-based biological materials: Molecular design and artificial production

A Miserez, J Yu, P Mohammadi - Chemical Reviews, 2023 - ACS Publications
Polymeric materials produced from fossil fuels have been intimately linked to the
development of industrial activities in the 20th century and, consequently, to the …

Aggregation-induced emission: together we shine, united we soar!

J Mei, NLC Leung, RTK Kwok, JWY Lam… - Chemical …, 2015 - ACS Publications
Light is of essential importance to the universe and humankind. Light has been, and
continues to be, one of the most fundamental and indispensable elements to life and society …

Changes in structure, rheological property and antioxidant activity of soy protein isolate fibrils by ultrasound pretreatment and EGCG

X Tong, J Cao, T Tian, B Lyu, L Miao, Z Lian, W Cui… - Food …, 2022 - Elsevier
Impacts of ultrasound pretreatment on the formation of soy protein fibrils, interaction of soy
protein fibrils and EGCG, rheological property and antioxidant activity of the complex, and …

Functional amyloids

D Otzen, R Riek - Cold Spring Harbor perspectives in …, 2019 - cshperspectives.cshlp.org
When protein/peptides aggregate, they usually form the amyloid state consisting of cross β-
sheet structure built by repetitively stacked β-strands forming long fibrils. Amyloids are …

The activities of amyloids from a structural perspective

R Riek, DS Eisenberg - Nature, 2016 - nature.com
The aggregation of proteins into structures known as amyloids is observed in many
neurodegenerative diseases, including Alzheimer's disease. Amyloids are composed of …

Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease

FA Zucca, J Segura-Aguilar, E Ferrari, P Muñoz… - Progress in …, 2017 - Elsevier
There are several interrelated mechanisms involving iron, dopamine, and neuromelanin in
neurons. Neuromelanin accumulates during aging and is the catecholamine-derived …

Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity

L Schnaider, S Brahmachari, NW Schmidt… - Nature …, 2017 - nature.com
Peptide-based supramolecular assemblies are a promising class of nanomaterials with
important biomedical applications, specifically in drug delivery and tissue regeneration …

Toxic PR poly-dipeptides encoded by the C9orf72 repeat expansion target LC domain polymers

Y Lin, E Mori, M Kato, S Xiang, L Wu, I Kwon… - Cell, 2016 - cell.com
Two complementary approaches were used in search of the intracellular targets of the toxic
PR poly-dipeptide encoded by the repeat sequences expanded in the C9orf72 form of …

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

M Jucker, LC Walker - Nature, 2013 - nature.com
For several decades scientists have speculated that the key to understanding age-related
neurodegenerative disorders may be found in the unusual biology of the prion diseases …

Amyloid polymorphism in the protein folding and aggregation energy landscape

J Adamcik, R Mezzenga - Angewandte Chemie International …, 2018 - Wiley Online Library
Protein folding involves a large number of steps and conformations in which the folding
protein samples different thermodynamic states characterized by local minima. Kinetically …