Conventional chemotherapeutics have been developed into clinically useful agents based
on their ability to preferentially kill malignant cells, generally owing to their elevated …

Following initial successes in melanoma treatment, immunotherapy has rapidly become
established as a major treatment modality for multiple types of solid cancers, including a …

Immunotherapy has become an established pillar of cancer treatment improving the
prognosis of many patients with a broad variety of hematological and solid malignancies …

Investigations into the interaction between radiotherapy and the host immune system have
uncovered new mechanisms that can potentially be exploited to improve the efficacy of …

Checkpoint blockade immunotherapy has received mainstream attention as a result of
striking and durable clinical responses in some patients with metastatic disease and a …

Purpose: Preoperative chemoradiotherapy (CRT) and surgical resection are the standard
treatment for locally advanced rectal cancer (LARC). Combining immune checkpoint …

Glioblastoma (GBM) is the most common primary brain tumor in adults an carries and carries
a terrible prognosis. The current regiment of surgical resection, radiation, and chemotherapy …

Radiotherapy is a major modality used to combat a wide range of cancers. Classical
radiobiology principles categorize ionizing radiation (IR) as a direct cytocidal therapeutic …

Lung cancer is currently the leading cause of cancer-related death in worldwide, non-small
cell lung cancer (NSCLC) accounts for about 85% of all lung cancers. Surgery, platinum …

Radiotherapy has been used for more than a hundred years to cure or locally control tumors.
Regression of tumors outside of the irradiated field was occasionally observed and is known …