The pathophysiology of glaucoma is complex, multifactorial and not completely understood.
Elevated intraocular pressure (IOP) and/or impaired retinal blood flow may cause initial optic …

Glaucoma is a common, complex, multifactorial neurodegenerative disease characterized
by progressive dysfunction and then loss of retinal ganglion cells, the output neurons of the …

Over 60 million people worldwide are diagnosed with glaucomatous optic neuropathy,
which is estimated to be responsible for 8.4 million cases of irreversible blindness globally …

Mitochondrial dysfunction and excessive inflammatory responses are both sufficient to
induce pathology in age-dependent neurodegenerations. However, emerging evidence …

Abstract Ketogenic diet (KD), the “High‐fat, low‐carbohydrate, adequate‐protein” diet
strategy, replacing glucose with ketone bodies, is effective against several diseases, from …

Damage to the optic nerve and the death of associated retinal ganglion cells (RGCs) by
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …

Background Glaucoma is a leading neurodegenerative disease affecting over 70 million
individuals worldwide. Early pathological events of axonal degeneration and retinopathy in …

Glaucoma is one of the leading causes of irreversible blindness in the world and remains a
major public health problem. To date, incomplete knowledge of this disease's …

Retinal ganglion cells (RGCs) are neurons of the visual system that are responsible for
transmitting signals from the retina to the brain via the optic nerve. Glaucoma is an optic …

Retinal ganglion cell (RGC) degeneration causes vision loss in patients with glaucoma, and
this has been generally considered to be irreversible due to RGC death. We question this …