Recomendaciones de «hacer» y «no hacer» en el tratamiento de los pacientes críticos ante la pandemia por coronavirus causante de COVID-19 de los Grupos de …

MAB Sanz, A Hernández-Tejedor, Á Estella… - Medicina intensiva, 2020 - Elsevier
El 11 de marzo de 2020 el director general de la Organización Mundial de la Salud (OMS)
declaró la enfermedad causada por el SARS-CoV-2 (COVID-19) como una pandemia. La …

Safety and efficacy of ciprofol vs. propofol for sedation in intensive care unit patients with mechanical ventilation: a multi-center, open label, randomized, phase 2 trial

Y Liu, X Yu, D Zhu, J Zeng, Q Lin, B Zang… - Chinese medical …, 2022 - journals.lww.com
Background: Ciprofol (HSK3486; Haisco Pharmaceutical Group Co., Ltd., Chengdu, China),
developed as a novel 2, 6-disubstituted phenol derivative showed similar tolerability and …

Efficacy and safety of ciprofol sedation in ICU patients with mechanical ventilation: a clinical trial study protocol

Y Liu, C Chen, N Liu, L Tong, Y Nie, J Wu, X Liu… - Advances in …, 2021 - Springer
Introduction From previous studies of pharmacodynamic data in mice, rats, beagle dogs and
mini pigs, frequently in direct comparison to induction doses of propofol, ciprofol produced a …

[HTML][HTML] Comparative risks and clinical outcomes of midazolam versus other intravenous sedatives in critically ill mechanically ventilated patients: A systematic review …

YX Chen, MH Ho - Intensive and Critical Care Nursing, 2025 - Elsevier
Objectives This systematic review synthesized literature evidence and compared
midazolam's risks and clinical outcomes with other sedatives in critically ill mechanically …

Recommendations of the Working Groups from the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC) for the management of …

MÁB Sanz, A Hernández-Tejedor, Á Estella… - Medicina Intensiva …, 2020 - Elsevier
Abstract On March 11, 2020, the Director-General of the World Health Organization (WHO)
declared the disease caused by SARS-CoV-2 (COVID-19) as a pandemic. The spread and …

Derivation and validation of an ensemble model for the prediction of agitation in mechanically ventilated patients maintained under light sedation

Z Zhang, J Liu, J Xi, Y Gong, L Zeng… - Critical Care Medicine, 2021 - journals.lww.com
OBJECTIVES: Light sedation is recommended over deep sedation for invasive mechanical
ventilation to improve clinical outcome but may increase the risk of agitation. This study …

Differential effects of gamma-aminobutyric acidergic sedatives on risk of post-extubation delirium in the ICU: A retrospective cohort study from a New England health …

O Azimaraghi, K Wongtangman… - Critical care …, 2022 - journals.lww.com
OBJECTIVES: To evaluate whether different gamma-aminobutyric acidergic (GABAergic)
sedatives such as propofol and benzodiazepines carry differential risks of post-extubation …

[HTML][HTML] Exploring the Role of Ketamine Sedation in Critically Ill Patients: A Comprehensive Review

S Banik, S Madavi - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Sedation management in critically ill patients is a critical component of intensive care,
aiming to balance the need for comfort and immobilization with preserving vital physiological …

[HTML][HTML] Molecular displacement approach for the electrochemical detection of protein-bound propofol

DC Ferrier, J Kiely, R Luxton - Sensing and Bio-Sensing Research, 2024 - Elsevier
Propofol is one of the principal drugs used for the sedation of patients undergoing
mechanical ventilation in intensive care units. The correct dosage of such sedative drugs is …

Changes in communication of end-of-life decisions in European ICUs from 1999 to 2016 (Ethicus-2)-a prospective observational study

CS Hartog, PA Maia, B Ricou, C Danbury, L Galarza… - Journal of critical …, 2022 - Elsevier
Purpose We investigated changes in communication practice about end-of-life decisions in
European ICUs over 16 years. Materials and methods This prospectively planned secondary …