Tumor formation and growth depend on various biological metabolism processes that are
distinctly different with normal tissues. Abnormal energy metabolism is one of the typical …

Nasopharyngeal carcinoma (NPC) is a malignant tumor of the nasopharynx mainly
characterized by geographic distribution and EBV infection. Metabolic reprogramming, one …

Neoplastic cells overexpress glucose transporters (GLUT), particularly GLUT1 and GLUT3,
to support altered metabolism. Hence, novel strategies are being explored to effectively …

Immune cells are one of the most versatile cell types, as they can tailor their metabolic
activity according to their required function. In response to diverse environmental cues …

Lysophosphatidic acid (LPA) is a small phospholipid that acts as an extracellular lipid
mediator. It promotes cancer progression by altering a wide array of cellular processes …

Purpose T-cell lymphomas, refer to a diverse set of lymphomas that originate from T-cells, a
type of white blood cell, with limited treatment options. This investigation aimed to assess the …

Bromopyruvate (3bp) is a small, highly reactive molecule formed by bromination of pyruvate.
In the year 2000, the antitumor properties of 3bp were discovered. Studies using animal …

Methyl jasmonate (MJ), a natural oxylipin, possesses a broad spectrum of antineoplastic
potential in vitro. However, its tumor growth impeding and chemo-potentiating action has not …

Malignant cells possess a unique metabolic machinery to endure unobstructed cell survival.
It comprises several levels of metabolic networking consisting of 1) upregulated expression …

Background Cancer has emerged as a systemic disease which targets various organs thus
challenging the overall physiology of the host. Recently, we have shown that hyperactive …