Dendritic cell regulation of T helper cells

X Yin, S Chen, SC Eisenbarth - Annual review of immunology, 2021 - annualreviews.org
As the professional antigen-presenting cells of the immune system, dendritic cells (DCs)
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …

[HTML][HTML] Wound healing: a cellular perspective

M Rodrigues, N Kosaric, CA Bonham… - Physiological …, 2018 - journals.physiology.org
Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE …

LJ Padrón, DM Maurer, MH O'Hara, EM O'Reilly… - Nature medicine, 2022 - nature.com
Chemotherapy combined with immunotherapy has improved the treatment of certain solid
tumors, but effective regimens remain elusive for pancreatic ductal adenocarcinoma …

Developmental cell programs are co-opted in inflammatory skin disease

G Reynolds, P Vegh, J Fletcher, EFM Poyner… - Science, 2021 - science.org
INTRODUCTION Human skin provides vital protection from water loss and from external
insult through structural adaptations and interplay with the innate and adaptive immune …

Transcriptional basis of mouse and human dendritic cell heterogeneity

CC Brown, H Gudjonson, Y Pritykin, D Deep… - Cell, 2019 - cell.com
Dendritic cells (DCs) play a critical role in orchestrating adaptive immune responses due to
their unique ability to initiate T cell responses and direct their differentiation into effector …

The dynamics of the skin's immune system

AV Nguyen, AM Soulika - International journal of molecular sciences, 2019 - mdpi.com
The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Cell adhesion molecules and their roles and regulation in the immune and tumor microenvironment

H Harjunpää, M Llort Asens, C Guenther… - Frontiers in …, 2019 - frontiersin.org
The immune system and cancer have a complex relationship with the immune system
playing a dual role in tumor development. The effector cells of the immune system can …

Dendritic cells and their role in immunotherapy

A Gardner, Á de Mingo Pulido, B Ruffell - Frontiers in immunology, 2020 - frontiersin.org
Despite significant advances in the field of cancer immunotherapy, the majority of patients
still do not benefit from treatment and must rely on traditional therapies. Dendritic cells have …

Dendritic cell subsets in T cell programming: location dictates function

SC Eisenbarth - Nature Reviews Immunology, 2019 - nature.com
Dendritic cells (DCs) can be viewed as translators between innate and adaptive immunity.
They integrate signals derived from tissue infection or damage and present processed …

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

S Chakarov, HY Lim, L Tan, SY Lim, P See, J Lum… - Science, 2019 - science.org
INTRODUCTION Resident tissue macrophages (RTMs) are a heterogeneous population of
immune cells occupying multiple tissue niches and exhibiting microenvironment-specific …