Atropselective partitioning of polychlorinated biphenyls in a HepG2 cell culture system: experimental and modeling results

CY Zhang, S Flor, G Ludewig… - Environmental science & …, 2020 - ACS Publications
Cell culture models are used to study the toxicity of polychlorinated biphenyls (PCBs);
however, it is typically unknown how much PCB enters the cells and, for chiral PCBs, if the …

Potential metabolic activation of a representative C4-alkylated polycyclic aromatic hydrocarbon retene (1-methyl-7-isopropyl-phenanthrene) associated with the …

M Huang, C Mesaros, LC Hackfeld… - Chemical research in …, 2017 - ACS Publications
Exposure to petrogenic polycyclic aromatic hydrocarbons (PPAHs) in the food chain is the
major human health hazard associated with the Deepwater Horizon oil spill. C4 …

Potential metabolic activation of representative alkylated polycyclic aromatic hydrocarbons 1-methylphenanthrene and 9-ethylphenanthrene associated with the …

M Huang, C Mesaros, LC Hackfeld… - Chemical research in …, 2017 - ACS Publications
Exposure to petrogenic polycyclic aromatic hydrocarbons (PPAHs) is the major human
health hazard associated with the Deepwater Horizon oil spill. Alkylated phenanthrenes are …

[HTML][HTML] Assessment of the In Vitro Phosphatidylinositol Glycan Class A (PIG-A) Gene Mutation Assay Using Human TK6 and Mouse Hepa1c1c7 Cell Lines

W Zhang, CA Miller, MJ Wilson - Journal of Xenobiotics, 2024 - mdpi.com
Gene mutations linked to diseases like cancer may be caused by exposure to environmental
chemicals. The X-linked phosphatidylinositol glycan class A (PIG-A) gene, required for …

Using precision environmental health principles in risk evaluation and communication of the deepwater horizon oil spill

D Jackson, M Huang, H Fernando… - … : A Journal of …, 2019 - journals.sagepub.com
This article provides a description of the rationale and processes adopted by the Gulf Coast
Health Alliance: Health Risks related to the Macondo Spill consortium to evaluate and …

Application of In-Vitro Phosphatidylinositol Glycan Class A (PIG-A) Gene Mutation Assay in Human TK6 Cell Line and Mouse HEPA1C1C7 Cell Line

W Zhang - 2024 - search.proquest.com
Gene mutations, particularly those associated with diseases like cancer, are often triggered
by environmental chemicals encountered in daily life. The X-linked Phosphatidylinositol …

Potential metabolic activation of a representative C2-alkylated polycyclic aromatic hydrocarbon 6-ethylchrysene associated with the deepwater horizon oil spill in …

M Huang, C Mesaros, S Zhang, IA Blair… - Chemical research in …, 2016 - ACS Publications
Exposure to polycyclic aromatic hydrocarbons (PAHs) is the major human health hazard
associated with the Deepwater Horizon oil spill. C2-Chrysenes are representative PAHs …

Polycyclic aromatic hydrocarbons and oxygenated polycyclic aromatic hydrocarbons (PAHs and Oxy-PAHs) in house dust samples in relation to smoking behavior in …

LE Azure - 2016 - search.proquest.com
Polycyclic aromatic hydrocarbons (PAHs) and their derivatives, oxygenated and nitrated
PAHs, are ubiquitous atmospheric pollutants with toxic, mutagenic, and carcinogenic …

Fractionation, Chemical Analysis, and In Vitro Testing Identify Bioactive Components in MC252 Crude Oil

E Overton, D Pangeni, M Wilson… - International Oil …, 2021 - meridian.allenpress.com
Crude oil is a complex mixture that includes polycyclic aromatic hydrocarbons (PAHs) as
one of its major components. The toxicity of some chemically substituted PAHs found in oil …

Toxicological Evaluation of Specific Polycyclic Aromatic Hydrocarbons and Other Oil Compounds from the Deepwater Horizon Oil Spill

AY Alqassim - 2019 - search.proquest.com
Crude oil is a complex mixture of chemicals with variable toxic properties. The Deepwater
Horizon oil (BP) spill introduced large amounts of these chemicals into the environment …