Nanomaterials for in vivo imaging

BR Smith, SS Gambhir - Chemical reviews, 2017 - ACS Publications
In vivo imaging, which enables us to peer deeply within living subjects, is producing
tremendous opportunities both for clinical diagnostics and as a research tool. Contrast …

[HTML][HTML] Pathology of pancreatic ductal adenocarcinoma: facts, challenges and future developments

I Esposito, B Konukiewitz, AM Schlitter… - World journal of …, 2014 - ncbi.nlm.nih.gov
Despite major improvements concerning its diagnosis and treatment, pancreatic ductal
adenocarcinoma (PDAC) remains an aggressive disease with an extremely poor prognosis …

44Sc: An Attractive Isotope for Peptide-Based PET Imaging

R Hernandez, HF Valdovinos, Y Yang… - Molecular …, 2014 - ACS Publications
The overexpression of integrin αvβ3 has been linked to tumor aggressiveness and
metastasis in several cancer types. Because of its high affinity, peptides containing the …

Targeted Cyclo [8] pyrrole-Based NIR-II Photoacoustic Tomography Probe for Suppression of Orthotopic Pancreatic Tumor Growth and Intra-abdominal Metastases

J Chen, R Chen, CV Chau, AC Sedgwick… - Journal of the …, 2024 - ACS Publications
Pancreatic cancer is highly lethal. New diagnostic and treatment modalities are desperately
needed. We report here that an expanded porphyrin, cyclo [8] pyrrole (CP), with a high …

Rodent models for human diseases

TF Vandamme - European journal of pharmacology, 2015 - Elsevier
One of the factors limiting the translation of knowledge from preclinical studies to the clinic
has been the limitations of in vivo diseases models. Except in the case of highly controlled …

6-Aminocaproic acid as a linker to improve near-infrared fluorescence imaging and photothermal cancer therapy of PEGylated indocyanine green

Q Hu, K Wang, L Qiu - Colloids and Surfaces B: Biointerfaces, 2021 - Elsevier
Clinical extensive application of indocyanine green (ICG) is limited by several drawbacks
such as poor bioenvironmental stability, aggregate propensity, and rapid elimination from …

Plectin-1 targeted dual-modality nanoparticles for pancreatic cancer imaging

X Chen, H Zhou, X Li, N Duan, S Hu, Y Liu, Y Yue… - …, 2018 - thelancet.com
Background Biomarker-targeted molecular imaging holds promise for early detection of
pancreatic cancer. The aim of this study was to design and evaluate a plectin-1 targeted …

Continued rapid growth in 68Ga applications: update 2013 to June 2014

I Velikyan - Journal of Labelled Compounds and …, 2015 - Wiley Online Library
The worldwide utilization of 68Ga‐radionuclide for the fundamental research and clinical
applications is growing exponentially. A broad range of 68Ga‐based imaging agents has …

Prospective of 68Ga Radionuclide Contribution to the Development of Imaging Agents for Infection and Inflammation

I Velikyan - Contrast Media & Molecular Imaging, 2018 - Wiley Online Library
During the last decade, the utilization of 68Ga for the development of imaging agents has
increased considerably with the leading position in the oncology. The imaging of infection …

Indocyanine green loaded hyaluronan-derived nanoparticles for fluorescence-enhanced surgical imaging of pancreatic cancer

B Qi, AJ Crawford, NE Wojtynek, MB Holmes… - … , Biology and Medicine, 2018 - Elsevier
Pancreatic ductal adenocarcinoma is highly lethal and surgical resection is the only
potential curative treatment for the disease. In this study, hyaluronic acid derived …