T Hideshima, PL Bergsagel, WM Kuehl, KC Anderson - Blood, 2004 - ashpublications.org
There appear to be 2 pathways involved in the early pathogenesis of premalignant monoclonal gammopathy of undetermined significance (MGUS) and malignant multiple …
Background and Aims Cancer‐associated fibroblasts (CAFs) are key players in multicellular, stromal‐dependent alterations leading to HCC pathogenesis. However, the intricate …
J Turkson - Expert opinion on therapeutic targets, 2004 - Taylor & Francis
Signal transducer and activator of transcription (STAT) proteins are latent cytoplasmic transcription factors that were discovered in the context of cytokine and growth factor …
G Salfi, F Casiraghi, G Remuzzi - Frontiers in immunology, 2023 - frontiersin.org
The pathogenetic mechanisms underlying the onset and the post-transplant recurrence of primary focal segmental glomerulosclerosis (FSGS) are complex and remain yet to be fully …
J Ge, L Xie, J Chen, S Li, H Xu, Y Lai, L Qiu… - Chinese journal of …, 2018 - Springer
Objectives To investigate the mechanism of Liuwei Dihuang Pill (六味地黄丸, LDP) in treating postmenopausal osteoporosis (PMOP) with Shen (Kidney) yin deficiency. Methods …
F Blanchard, L Duplomb, M Baud'huin… - Cytokine & growth factor …, 2009 - Elsevier
Many factors such as vitamins, hormones and cytokines, control bone metabolism and remodeling. Cytokines of the interleukin-6 family, by acting on bone cells (ie osteoblasts and …
M Mancino, E Ametller, P Gascón… - Biochimica et Biophysica …, 2011 - Elsevier
Nerve fibers accompany blood and lymphatic vessels all over the body. An extensive amount of knowledge has been obtained with regard to tumor angiogenesis and tumor …
The nervous system plays a central role in regulating the stem cell niche in many organs, and thereby pivotally modulates development, homeostasis, and plasticity. A similarly …
Cancer-associated fibroblasts (CAF) have been reported to support tumor progression by a variety of mechanisms. However, their role in the progression of non–small cell lung cancer …