[HTML][HTML] Extracellular vesicle-loaded hydrogels for tissue repair and regeneration

Y Ju, Y Hu, P Yang, X Xie, B Fang - Materials Today Bio, 2023 - Elsevier
Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles
secreted by cells that play important biological roles. Mesenchymal stem cells are a class of …

3D cell culture systems: tumor application, advantages, and disadvantages

O Habanjar, M Diab-Assaf, F Caldefie-Chezet… - International journal of …, 2021 - mdpi.com
The traditional two-dimensional (2D) in vitro cell culture system (on a flat support) has long
been used in cancer research. However, this system cannot be fully translated into clinical …

Magnetically steerable bacterial microrobots moving in 3D biological matrices for stimuli-responsive cargo delivery

MB Akolpoglu, Y Alapan, NO Dogan, SF Baltaci… - Science …, 2022 - science.org
Bacterial biohybrids, composed of self-propelling bacteria carrying micro/nanoscale
materials, can deliver their payload to specific regions under magnetic control, enabling …

A comprehensive review on collagen type I development of biomaterials for tissue engineering: From biosynthesis to bioscaffold

IN Amirrah, Y Lokanathan, I Zulkiflee, MFMR Wee… - Biomedicines, 2022 - mdpi.com
Collagen is the most abundant structural protein found in humans and mammals, particularly
in the extracellular matrix (ECM). Its primary function is to hold the body together. The …

Collagen-and hyaluronic acid-based hydrogels and their biomedical applications

Q Xu, JE Torres, M Hakim, PM Babiak, P Pal… - Materials Science and …, 2021 - Elsevier
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

[HTML][HTML] Collagen-based biomaterials for bone tissue engineering

Y Li, Y Liu, R Li, H Bai, Z Zhu, L Zhu, C Zhu, Z Che… - Materials & Design, 2021 - Elsevier
In recent years, there has been increasing interest in using biomimetic materials for bone
tissue engineering. However, the high immunogenicity and low mechanical properties of …

[HTML][HTML] A tough act to follow: Collagen hydrogel modifications to improve mechanical and growth factor loading capabilities

SO Sarrigiannidis, JM Rey, O Dobre… - Materials Today Bio, 2021 - Elsevier
Collagen hydrogels are among​ the most well-studied platforms for drug delivery and in situ
tissue engineering, thanks to their low cost, low immunogenicity, versatility, biocompatibility …

Engineered materials for organoid systems

MJ Kratochvil, AJ Seymour, TL Li, SP Paşca… - Nature Reviews …, 2019 - nature.com
Organoids are 3D cell culture systems that mimic some of the structural and functional
characteristics of an organ. Organoid cultures provide the opportunity to study organ-level …

Biomaterials for articular cartilage tissue engineering: Learning from biology

AR Armiento, MJ Stoddart, M Alini, D Eglin - Acta biomaterialia, 2018 - Elsevier
Articular cartilage is commonly described as a tissue that is made of up to 80% water, is
devoid of blood vessels, nerves, and lymphatics, and is populated by only one cell type, the …

Hydrogel as a biomaterial for bone tissue engineering: A review

S Yue, H He, B Li, T Hou - Nanomaterials, 2020 - mdpi.com
Severe bone damage from diseases, including extensive trauma, fractures, and bone
tumors, cannot self-heal, while traditional surgical treatment may bring side effects such as …