Heterotopic ossification (HO) is the formation of pathological bone in ectopic sites and it can
have serious consequences for functional outcomes. For many years, its main clinical …

Abstract Activin receptor-like kinase-2 (ALK2), the product of ACVR1, is a member of the
type I bone morphogenetic protein (BMP) receptor family. ALK2 exerts key and non …

Bone morphogenetic protein (BMP) signaling is a critical regulator of cartilage differentiation
and endochondral ossification. Gain‐of‐function mutations in ALK2, a type I BMP receptor …

The successful completion of the Human Genome Project (HGP) was an unprecedented
scientific advance that has become an invaluable resource in the search for genes that …

Objective To carefully assess skeletal lesions in close environment context in order to
evaluate whether skeletal fluorosis was present in individuals living in the prehistoric …

Two domestic shorthair cats, 1 intact female and 1 intact male, presented with progressive
limb lameness and digital deformities at 4 and 6 months of age. Stiffness and swelling of the …

Background: Trismus is a problem commonly encountered by the dental practitioner. It has a
number of potential causes, and its treatment will depend on the cause. However, there are …

The need to quantify physicochemical properties of mineralisation spans many fields.
Clinicians, mineralisation researchers, and bone tissue bioengineers need to be able to …

Classification in Paralympic athletics aims to promote participation by people with
disabilities by minimising the impact of impairment on the outcome of competition. Achieving …