Neuropsychiatric research has been impeded by limited access to human brain tissue,
especially from early stages of neurodevelopment when the pathophysiology of many …

Human telencephalon is an evolutionarily advanced brain structure associated with many
uniquely human behaviors and disorders. However, cell lineages and molecular pathways …

Multiple molecular pathways and cellular processes have been implicated in the
neurobiology of autism and other neurodevelopmental conditions. There is a current focus …

Mutations in many synaptic genes are associated with autism spectrum disorders (ASD),
suggesting that synaptic dysfunction is a key driver of ASD pathogenesis. Among these …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder whose hallmarks are
social deficits, language impairment, repetitive behaviors, and sensory alterations. It has …

On September 27, 2023, the CureSHANK nonprofit foundation sponsored a conference in
Boston, Massachusetts, to identify gaps in knowledge surrounding SHANK3-related …

Autism spectrum disorders represent a diverse etiological spectrum that converge on a
syndrome characterized by discrepant deficits in developmental domains often highlighted …

Over the past decade, tremendous progress has been made in defining autism spectrum
disorder (ASD) as a disorder of brain connectivity. Indeed, whole-brain imaging studies …

Autism spectrum disorder (ASD) includes a group of multifactorial neurodevelopmental
disorders characterized by impaired social communication, social interaction, and repetitive …

Autism spectrum disorder (ASD) is associated with a range of abnormalities characterized
by deficits in socialization, communication, repetitive behaviors, and restricted interests. We …