Chiral stationary phases for liquid chromatography: recent developments

J Teixeira, ME Tiritan, MMM Pinto, C Fernandes - Molecules, 2019 - mdpi.com
The planning and development of new chiral stationary phases (CSPs) for liquid
chromatography (LC) are considered as continuous and evolutionary issues since the …

Structure control of polysaccharide derivatives for efficient separation of enantiomers by chromatography

T Ikai, Y Okamoto - Chemical Reviews, 2009 - ACS Publications
Chirality is a ubiquitous feature in living systems. Today, it is widely recognized that many
biologically interesting compounds, such as drugs, agrochemicals, food additives, and …

Enantioseparation of selected chiral sulfoxides using polysaccharide-type chiral stationary phases and polar organic, polar aqueous–organic and normal-phase …

B Chankvetadze, C Yamamoto, Y Okamoto - Journal of chromatography A, 2001 - Elsevier
HPLC enantioseparation of selected chiral sulfoxides was studied using cellulose and
amylose phenylcarbamate derivatives as chiral stationary phases (CSPs). The contributions …

Polysaccharides chiral stationary phases in liquid chromatography

I Ali, K Saleem, I Hussain, VD Gaitonde… - Separation & …, 2009 - Taylor & Francis
Chiral resolution has achieved an independent identity in the separation sciences and
polysaccharide CSPs are viewed as effective and efficient CSPs due to their many unique …

Polysaccharide-based chiral LC columns

E Yashima, C Yamamoto, Y Okamoto - Synlett, 1998 - thieme-connect.com
Liquid chromatographic (LC) enantioseparations of various racemates on polysaccharide-
based chiral stationary phases (CSPs) are mainly described. The wide applicability and …

Chiral enantioresolution of cathinone derivatives present in “legal highs”, and enantioselectivity evaluation on cytotoxicity of 3, 4-methylenedioxypyrovalerone (MDPV)

B Silva, C Fernandes, ME Tiritan, MMM Pinto… - Forensic toxicology, 2016 - Springer
Recently, great interest has been focused on synthetic cathinones since their consumption
has increased exponentially. All synthetic cathinones exist as chiral molecules; the …

Enantiomeric determination of pantoprazole in human plasma by multidimensional high-performance liquid chromatography

QB Cass, ALG Degani, NM Cassiano… - … of Chromatography B, 2002 - Elsevier
Multidimensional HPLC is a powerful tool for the analysis of samples of a high degree of
complexity. This work reports the use of multidimensional HPLC by coupling a RAM column …

Investigation of the enantioselective separations of α-alkylarylcarboxylic acids on an amylose tris (3, 5-dimethylphenylcarbamate) chiral stationary phase using …

TD Booth, IW Wainer - Journal of Chromatography A, 1996 - Elsevier
A series of 28 chiral α-alkyl arylcarboxylic acids were chromatographed on an amylose tris
(3, 5-dimethylphenylcarbamate) chiral stationary phase (AD-CSP). The retention data were …

Enantioselective biodegradation of pharmaceuticals, alprenolol and propranolol, by an activated sludge inoculum

AR Ribeiro, CM Afonso, PML Castro… - … and environmental safety, 2013 - Elsevier
Biodegradation of chiral pharmaceuticals in the environment can be enantioselective. Thus
quantification of enantiomeric fractions during the biodegradation process is crucial for …

New chiral derivatives of xanthones: Synthesis and investigation of enantioselectivity as inhibitors of growth of human tumor cell lines

C Fernandes, K Masawang, ME Tiritan, E Sousa… - Bioorganic & medicinal …, 2014 - Elsevier
A highly efficient and practical methodology for synthesis of new chiral derivatives of
xanthones (CDXs) in enantiomerically pure form has been developed. According to this …