Sex differences in biological aging with a focus on human studies
S Hägg, J Jylhävä - Elife, 2021 - elifesciences.org
Aging is a complex biological process characterized by hallmark features accumulating over
the life course, shaping the individual's aging trajectory and subsequent disease risks. There …
the life course, shaping the individual's aging trajectory and subsequent disease risks. There …
Biological age predictors
J Jylhävä, NL Pedersen, S Hägg - EBioMedicine, 2017 - thelancet.com
The search for reliable indicators of biological age, rather than chronological age, has been
ongoing for over three decades, and until recently, largely without success. Advances in the …
ongoing for over three decades, and until recently, largely without success. Advances in the …
Accelerated biological aging in COVID-19 patients
Chronological age is a risk factor for SARS-CoV-2 infection and severe COVID-19. Previous
findings indicate that epigenetic age could be altered in viral infection. However, the …
findings indicate that epigenetic age could be altered in viral infection. However, the …
Association of telomere length with risk of disease and mortality
CV Schneider, KM Schneider, A Teumer… - JAMA internal …, 2022 - jamanetwork.com
Importance Telomeres protect DNA from damage. Because they shorten with each mitotic
cycle, leukocyte telomere length (LTL) serves as a mitotic clock. Reduced LTL has been …
cycle, leukocyte telomere length (LTL) serves as a mitotic clock. Reduced LTL has been …
Determinants of telomere length across human tissues
K Demanelis, F Jasmine, LS Chen, M Chernoff, L Tong… - Science, 2020 - science.org
INTRODUCTION Telomeres are DNA-protein complexes located at the end of chromosomes
that protect chromosome ends from degradation and fusion. The DNA component of …
that protect chromosome ends from degradation and fusion. The DNA component of …
Association between the Oxidative Balance Score and Telomere Length from the National Health and Nutrition Examination Survey 1999‐2002
W Zhang, SF Peng, L Chen, HM Chen… - Oxidative medicine …, 2022 - Wiley Online Library
Purpose. Leukocyte telomere length (LTL) is an important biomarker of aging. The oxidative
balance score (OBS) is used to assess the oxidative stress‐related exposures of diet and …
balance score (OBS) is used to assess the oxidative stress‐related exposures of diet and …
Telomere biology and human phenotype
KJ Turner, V Vasu, DK Griffin - Cells, 2019 - mdpi.com
Telomeres are nucleoprotein structures that cap the end of each chromosome arm and
function to maintain genome stability. The length of telomeres is known to shorten with each …
function to maintain genome stability. The length of telomeres is known to shorten with each …
The aging cardiovascular system: understanding it at the cellular and clinical levels
Cardiovascular disease (CVD) presents a great burden for elderly patients, their caregivers,
and health systems. Structural and functional alterations of vessels accumulate throughout …
and health systems. Structural and functional alterations of vessels accumulate throughout …
Mediterranean diet and health status: Active ingredients and pharmacological mechanisms
L Schwingshackl, J Morze… - British journal of …, 2020 - Wiley Online Library
The Mediterranean diet (MedDiet) is one of the most widely described and evaluated dietary
patterns in scientific literature. It is characterized by high intakes of vegetables, legumes …
patterns in scientific literature. It is characterized by high intakes of vegetables, legumes …
Association between telomere length and risk of cancer and non-neoplastic diseases: a Mendelian randomization study
Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …