Gliflozins are a novel class of oral anti-diabetic drugs, acting as inhibitors of sodium-glucose
co-transporters (SGLTs) through the proximal convoluted tubules (PCT) and intestinal …

Niacin (also known as “vitamin B3” or “vitamin PP”) includes two vitamers (nicotinic acid and
nicotinamide) giving rise to the coenzymatic forms nicotinamide adenine dinucleotide (NAD) …

Neurodegenerative diseases represent some of the most devastating neurological
disorders, characterized by progressive loss of the structure and function of neurons. Current …

Neurodegenerative diseases are characterized by the progressive loss of neurons in
different regions of the nervous system. Alzheimer's disease (AD) and Parkinson's disease …

Mitochondria-mediated oxidative stress and apoptosis contribute greatly to early brain injury
(EBI) following subarachnoid hemorrhage (SAH). This study hypothesized that activation of …

Citicoline is a chemical compound involved in the synthesis of cell membranes. It also has
other, not yet explained functions. Research on the use of citicoline is conducted in …

Diabetes predisposes to cognitive decline leading to dementia and is associated with
decreased brain NAD+ levels. This has triggered an intense interest in boosting …

High-caloric diet and physical inactivity predispose individuals to obesity and diabetes,
which are risk factors of hippocampal neurodegeneration and cognitive deficits. Along with …

Abstract Purpose of Review This review examines the linked pathophysiology of Alzheimer's
disease/related dementia (AD/ADRD) and bone disorders like osteoporosis. The emphasis …

Abstract Piceatannol (PCN), a SIRT1 activator, regulates multiple oxidative stress
mechanism and has anti-inflammatory potential in various inflammatory conditions …