With almost 20 million new cases per year, cancer constitutes one of the most important
challenges for public health systems. Unlike traditional chemotherapy, targeted anti-cancer …

Fibroblast growth factor receptors (FGFRs) in response to fibroblast growth factors (FGFs)
transmit signals across the cell membrane, regulating important cellular processes, like …

Peritoneal spread is the primary mechanism of metastasis of ovarian cancer, and survival of
ovarian cancer cells in the peritoneal cavity as nonadherent spheroids and their adherence …

Here, we demonstrate how array-based label-free biosensors can be applied to the
multiplexed interaction analysis of large panels of analyte/ligand pairs, such as the epitope …

Approximately 30 therapeutic monoclonal antibodies have already been approved for
cancers and inflammatory diseases, and monoclonal antibodies continue to be one of the …

Modern anti-HER2 antibody therapy tends to exploit a panel of different antibodies against
different epitopes on the antigen. For this aim, nanobodies are very striking targeting agents …

Cellular morphology has recently been indicated as a powerful indicator of cellular function.
The analysis of cell shape has evolved from rudimentary forms of microscopic visual …

General properties of the family of tyrosine kinase ERBB receptors are considered in
connection with their role in the generation of cascades of signal transduction in normal and …

Рассмотрены свойства семейства тирозинкиназных ERBB рецепторов и определена
их роль в генерации каскадных процессов передачи сигнала в живой клетке в норме и …

Patients with metastatic melanoma bearing V600 mutations in BRAF oncogene clinically
benefit from the treatment with BRAF inhibitors alone or in combination with MEK inhibitors …