Innate immunity is essential for the host against pathogens, cancer, and autoimmunity. The
innate immune system encodes many sensor, adaptor, and effector proteins and relies on …

Nucleic acid sensing is involved in viral infections, immune response-related diseases, and
therapeutics. Based on the composition of nucleic acids, nucleic acid sensors are defined as …

ZBP1 senses viral Z-RNAs to induce necroptotic cell death to restrain viral infection. ZBP1 is
also thought to recognize host cell-derived Z-RNAs to regulate organ development and …

Abstract Cyclic GMP‐AMP synthase (cGAS) is a double‐stranded DNA (dsDNA) sensor that
functions in the innate immune system. Upon binding dsDNA, cGAS and dsDNA form phase …

Stress granules (SGs) are cytoplasmic condensates that often form as part of the cellular
antiviral response. Despite the growing interest in understanding the interplay between SGs …

Stress granules (SGs) constitute a signaling hub that plays a critical role in type I interferon
responses. Here, we report that growth arrest and DNA damage-inducible beta (Gadd45β) …

The cGAS-STING signaling plays an integral role in the host immune response, and the
abnormal activation of cGAS-STING is highly related to various autoimmune diseases …

Adjuvants are of critical value in vaccine development as they act on enhancing
immunogenicity of antigen and inducing long‐lasting immunity. However, there are only a …

As a key dsDNA recognition receptor, cyclic guanosine monophosphate (GMP)-AMP
synthase (cGAS) plays a vital role in innate immune responses. Activated cGAS, by sensing …

Biomolecular condensates are membraneless organelles formed through liquid–liquid
phase separation. Innate immunity is essential to host defense against infections, but …