Malaria is a very destructive and lethal parasitic disease that causes significant mortality
worldwide, resulting in the loss of millions of lives annually. It is an infectious disease …

Protozoan parasite infection causes severe diseases in humans and animals, leading to
tremendous economic and medical pressure. Natural immunity is the first line of defence …

We herein report an efficient and green aerobic radical cascade reaction of o-
vinylphenylisocyanides with thiols to access a broad range of 2-thio-substituted quinolines …

Malaria is a widespread infectious disease, causing nearly 247 million cases in 2021. The
absence of a broadly effective vaccine and rapidly decreasing effectiveness of most of the …

Currently, artemisinin-based combination therapy is recommended as first-line treatment of
uncomplicated falciparum malaria. Arylamino alcohols (AAAs) such as mefloquine (MQ) are …

We herein report the design and synthesis of a new class of quinoxaline-benzimidazole
hybrids based on the molecular hybridization concept and evaluation of their in vitro …

A series of novel 2, 9-bis [(substituted-aminomethyl)]-4, 7-phenyl-1, 10-phenanthroline
derivatives was designed, synthesized, and evaluated in vitro against three protozoan …

By taking into account our previously described series of 1, 3, 5-tris [(4-(substituted-
aminomethyl) phenyl) methyl] benzene compounds, we have now designed, prepared, and …

A series of novel diaminopyrimidines containing pinane moieties were synthesized via an
efficient methodology starting from pinane‐based aminoalcohols, aminodiols and 2, 4 …

The JFH coupling constants in fluorinated amino alcohols were investigated through
experimental and theoretical approaches. The experimental JFH couplings were only …