Tumour growth is accompanied by tumour evasion of the immune system, a process that is
facilitated by immune checkpoint molecules such as programmed cell death protein 1 (PD1) …

Follicular lymphoma (FL) is a systemic neoplasm of the lymphoid tissue displaying germinal
centre (GC) B cell differentiation. FL represents~ 5% of all haematological neoplasms and …

Human IgG is the most abundant glycoprotein in serum and is crucial for protective
immunity. In addition to conserved IgG Fc glycans,∼ 15–25% of serum IgG contains glycans …

The HVEM (TNFRSF14) receptor gene is among the most frequently mutated genes in
germinal center lymphomas. We report that loss of HVEM leads to cell-autonomous …

Follicular lymphoma (FL) is the most common indolent non-Hodgkin lymphoma in the
Western hemisphere. After decades of stagnation, the natural history of FL appears to have …

Most patients with follicular lymphoma (FL) experience multiple relapses necessitating
subsequent lines of therapy. Ibrutinib, a Bruton tyrosine kinase (BTK) inhibitor approved for …

Follicular lymphoma (FL) is the most frequent indolent B cell lymphoma and is still
considered to be incurable. In recent years, whole-exome sequencing studies of large …

A hallmark of B-cell immunity is the generation of a diverse repertoire of antibodies from a
limited set of germline V (D) J genes. This repertoire is usually defined in terms of amino …

The B cell receptor (BCR) pathway has been identified as a potential therapeutic target in a
number of common B cell malignancies, including chronic lymphocytic leukemia, diffuse …

Granulomatous slack skin (GSS) is an extremely rare subtype of cutaneous T‐cell lymphoma
accompanied by an abundant number of macrophages and is clinically characterized by the …