A new edition of the WHO classification of tumours of the CNS was published in 2021.
Although the previous edition of this classification was published just 5 years earlier, in …

Advances in our understanding of the biological basis and molecular characteristics of
ependymal tumors since the latest iteration of the World Health Organization (WHO) …

Abstract cIMPACT‐NOW (the Consortium to Inform Molecular and Practical Approaches to
CNS Tumor Taxonomy) was established to evaluate and make practical recommendations …

Abstract Purpose of Review To review state of art and relevant advances in the molecular
genetics and management of ependymomas of children and adults. Recent Findings …

Good and effective treatment in radiotherapy requires careful consideration of the complex
variables involved as well as critical assessment of the techniques. This new edition of an …

Ependymomas are rare central nervous system tumours that can arise in the brain's
supratentorial region or posterior fossa, or in the spinal cord. In 1924, Percival Bailey …

Simple Summary Childhood cancers are mostly of unknown etiology and represent
devastating diagnoses. The clinical benefits of steadily increasing tumor control and survival …

More than 60% of supratentorial ependymomas harbor a ZFTA–RELA (ZRfus) gene fusion
(formerly C11orf95–RELA). To study the biology of ZRfus, we developed an autochthonous …

Abstract Background Within PF-EPN-A, 1q gain is a marker of poor prognosis, however, it is
unclear if within PF-EPN-A additional cytogenetic events exist which can refine risk …

Central nervous system (CNS) tumors are the most common solid tumor in pediatrics,
accounting for approximately 25% of all childhood cancers, and the second most common …