Recreating human organ–level function in vitro is a rapidly evolving field that integrates tissue engineering, stem cell biology, and microfluidic technology to produce 3D organoids …
VS Shirure, Y Bi, MB Curtis, A Lezia… - Lab on a Chip, 2018 - pubs.rsc.org
Most cancer treatment strategies target cell proliferation, angiogenesis, migration, and intravasation of tumor cells in an attempt to limit tumor growth and metastasis. An in vitro …
DTT Phan, X Wang, BM Craver, A Sobrino, D Zhao… - Lab on a Chip, 2017 - pubs.rsc.org
There is a growing awareness that complex 3-dimensional (3D) organs are not well represented by monolayers of a single cell type–the standard format for many drug screens …
The generation of functional, 3D vascular networks is a fundamental prerequisite for the development of many future tissue engineering‐based therapies. Current approaches in …
B Debuc, DM Smadja - Stem cell reviews and reports, 2021 - Springer
SARS-CoV-2 viruses are positive single-stranded RNA viruses, whose infection can be asymptomatic or lead to the coronavirus disease 2019 (Covid-19). Covid-19 is a respiratory …
BD Plouffe, SK Murthy, LH Lewis - Reports on Progress in …, 2014 - iopscience.iop.org
Magnetic sorting using magnetic beads has become a routine methodology for the separation of key cell populations from biological suspensions. Due to the inherent ability of …
Tissue engineering has been an active field of research for several decades now. However, the amount of clinical applications in the field of tissue engineering is still limited. One of the …
For 3D bioprinted tissues to be scaled-up to clinically relevant sizes, effective prevascularisation strategies are required to provide the necessary nutrients for normal …
MC Yoder - Cold Spring Harbor perspectives in …, 2012 - perspectivesinmedicine.cshlp.org
Human endothelial progenitor cells (EPCs) have been generally defined as circulating cells that express a variety of cell surface markers similar to those expressed by vascular …