Ocular drug delivery: a comprehensive review
The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …
Candida Biofilm Eye Infection: Main Aspects and Advance in Novel Agents as Potential Source of Treatment
F Petrillo, M Sinoca, AM Fea, M Galdiero, A Maione… - Antibiotics, 2023 - mdpi.com
Fungi represent a very important cause of microbial eye infections, especially in tropical and
developing countries, as they could cause sight-threating disease, such as keratitis and …
developing countries, as they could cause sight-threating disease, such as keratitis and …
Transdermal application of diacerin loaded-terpene enriched invasomes: an approach to augment anti-edema and nociception inhibition activity
This study aimed to formulate diacerein loaded terpene-enriched invasomes (DCN-TINV) to
fulfill a fruitful management of osteoarthritis. A 23 factorial design was adopted, including A …
fulfill a fruitful management of osteoarthritis. A 23 factorial design was adopted, including A …
Engineered lecithin-based proniosomes for enhanced trans-tympanic permeation: In vitro, microbiological, ex vivo and in vivo evaluation
Otitis media is an acute illness that specifically targets the middle ear. It affects around one-
third of the pediatric population in the US. This study aimed to develop lecithin-based …
third of the pediatric population in the US. This study aimed to develop lecithin-based …
Capped flexosomes for prominent anti-inflammatory activity: development, optimization, and ex vivo and in vivo assessments
This study aimed to formulate diacerein (DCN)-loaded flexosomes for enhanced efficacy
against osteoarthritis. A 23 D-optimal design was employed, investigating the impact of …
against osteoarthritis. A 23 D-optimal design was employed, investigating the impact of …
Incorporation of Inclusion Complexes in the Dissolvable Microneedle Ocular Patch System for the Efficiency of Fluconazole in the Therapy of Fungal Keratitis
U Mahfufah, MA Sya'ban Mahfud… - … Applied Materials & …, 2024 - ACS Publications
Fluconazole (FNL) is one of the first-line treatments for fungal keratitis as it is an effective
broad-spectrum antimicrobial commonly administered orally or topically. However, FNL has …
broad-spectrum antimicrobial commonly administered orally or topically. However, FNL has …
A comprehensive review on recent nanosystems for enhancing antifungal activity of fenticonazole nitrate from different routes of administration
This review aims to comprehensively highlight the recent nanosystems enclosing
Fenticonazole nitrate (FTN) and to compare between them regarding preparation …
Fenticonazole nitrate (FTN) and to compare between them regarding preparation …
Limonene-Enriched Ultra-Structural Cubosomes to Augment Ocular Delivery of a Poorly Water Soluble Anti-Fungal Drug: Fabrication, Characterization, Statistical …
The target of this investigation was to obtain the composition of the optimized Fenticonazole
nitrate (FCN)-loaded cubosomal formula that can prolong precorneal retention, increase …
nitrate (FCN)-loaded cubosomal formula that can prolong precorneal retention, increase …
Recent updates on drug delivery approaches for improved ocular delivery with an insight into nanostructured drug delivery carriers for anterior and posterior segment …
Ocular diseases have a major impact on patient's vision and quality of life, with
approximately 2.2 billion people have visual impairment worldwide according to the findings …
approximately 2.2 billion people have visual impairment worldwide according to the findings …
Microneedles deliver drugs to ophthalmic tissue
Drug delivery to the eyes is difficult, and the drugs have low bioavailability because of the
natural physiological barrier of this organ. Ocular diseases have affected millions of people …
natural physiological barrier of this organ. Ocular diseases have affected millions of people …