Abstract 3D bioprinting is a pioneering technology that enables fabrication of biomimetic,
multiscale, multi-cellular tissues with highly complex tissue microenvironment, intricate …

BACKGROUND To provide the optimal milieu for implantation and fetal development, the
female reproductive system must orchestrate uterine dynamics with the appropriate …

Emerging additive manufacturing techniques enable investigation of the effects of pore
geometry on cell behavior and function. Here, we 3D print microporous hydrogel scaffolds to …

The endocrine system dynamically controls tissue differentiation and homeostasis, but has
not been studied using dynamic tissue culture paradigms. Here we show that a microfluidic …

BACKGROUND Chemotherapy treatment in premenopausal women is associated with an
increased risk of premature ovarian failure (POF) but the exact mechanism through which …

Traditional methods of cell growth and manipulation on 2-dimensional (2D) surfaces have
been shown to be insufficient for new challenges of cell biology and biochemistry, as well as …

The classical view of ovarian follicle development is that it is regulated by the hypothalamic-
pituitary-ovarian axis, in which gonadotropin-releasing hormone (GnRH) controls the …

In vitro follicle growth is a potential approach to preserve fertility for young women who are
facing a risk of premature ovarian failure (POF) caused by radiation or chemotherapy. Our …

The increasing number of young survivors of cancer who have favorable outcomes
necessitates planning for the preservation of fertility, which may mean modifying the strategy …

The major goal of this review is to summarize recent exciting findings that have been
published within the past 10 years that, to our knowledge, have not been presented in detail …