Incidence and mortality of hospital-and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis

C Fleischmann-Struzek, L Mellhammar, N Rose… - Intensive care …, 2020 - Springer
Purpose To investigate the global burden of sepsis in hospitalized adults by updating and
expanding a systematic review and meta-analysis and to compare findings with recent …

How the COVID-19 pandemic will change the future of critical care

YM Arabi, E Azoulay, HM Al-Dorzi, J Phua… - Intensive care …, 2021 - Springer
Abstract Coronavirus disease 19 (COVID-19) has posed unprecedented healthcare system
challenges, some of which will lead to transformative change. It is obvious to healthcare …

Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial

K Ali, T Azher, M Baqi, A Binnie, S Borgia, FM Carrier… - Cmaj, 2022 - Can Med Assoc
Background: The role of remdesivir in the treatment of patients in hospital with COVID-19
remains ill defined in a global context. The World Health Organization Solidarity randomized …

Balanced crystalloids versus saline in critically ill adults

MW Semler, WH Self, JP Wanderer… - … England Journal of …, 2018 - Mass Medical Soc
Background Both balanced crystalloids and saline are used for intravenous fluid
administration in critically ill adults, but it is not known which results in better clinical …

Mechanical ventilation in COVID-19: interpreting the current epidemiology

H Wunsch - American Journal of Respiratory and Critical Care …, 2020 - atsjournals.org
The world is scrutinizing every cohort and every outcome for patients with coronavirus
disease (COVID-19), particularly the most critically ill who are receiving mechanical …

The epidemiology of sepsis in Brazilian intensive care units (the Sepsis PREvalence Assessment Database, SPREAD): an observational study

FR Machado, AB Cavalcanti, FA Bozza… - The Lancet Infectious …, 2017 - thelancet.com
Background The sepsis burden on acute care services in middle-income countries is a
cause for concern. We estimated incidence, prevalence, and mortality of sepsis in adult …

Critical care bed capacity in Asian countries and regions

J Phua, MO Faruq, AP Kulkarni, IS Redjeki… - Critical care …, 2020 - journals.lww.com
Objective: To assess the number of adult critical care beds in Asian countries and regions in
relation to population size. Design: Cross-sectional observational study. Setting: Twenty …

The surviving sepsis campaign bundles and outcome: results from the international multicentre prevalence study on sepsis (the IMPreSS study)

A Rhodes, G Phillips, R Beale, M Cecconi… - Intensive care …, 2015 - Springer
Introduction Despite evidence demonstrating the value of performance initiatives, marked
differences remain between hospitals in the delivery of care for patients with sepsis. The …

Adult ICU triage during the coronavirus disease 2019 pandemic: who will live and who will die? Recommendations to improve survival

CL Sprung, GM Joynt, MD Christian… - Critical care …, 2020 - journals.lww.com
Objectives: Coronavirus disease 2019 patients are currently overwhelming the world's
healthcare systems. This article provides practical guidance to front-line physicians forced to …

Mortality after surgery in Europe: a 7 day cohort study

RM Pearse, RP Moreno, P Bauer, P Pelosi, P Metnitz… - The Lancet, 2012 - thelancet.com
Background Clinical outcomes after major surgery are poorly described at the national level.
Evidence of heterogeneity between hospitals and health-care systems suggests potential to …