Lung cancer is the leading cause of cancer-related death across the world. Unlike lung
adenocarcinoma, patients with lung squamous cell carcinoma (LSCC) have not benefitted …

Cancer is a heavy burden for humans across the world with high morbidity and mortality.
Transcription factors including sex determining region Y (SRY)-related high-mobility group …

SOX2 is a well-characterized pluripotent factor that is essential for stem cell self-renewal,
reprogramming, and homeostasis. The cellular levels of SOX2 are precisely regulated by a …

SOX2 is a gene that encodes for a transcription factor belonging to the SOX gene family and
contains a high-mobility group (HMG) domain, which permits highly specific DNA binding …

Cancer is a leading cause of death worldwide and around 10 million deaths in 2020 were
related to cancer. There are a number of therapeutic modalities for cancer such as …

Abstract The transcription factor Yin Yang 1 (YY1) is frequently overexpressed in cancerous
tissues compared to normal tissues and has regulatory roles in cell proliferation, cell …

New strategies are needed to predict and overcome metastatic progression and therapy
resistance in prostate cancer. One potential clinical target is the stem cell transcription factor …

Specific targeting and cellular internalization are key properties for carriers of antitumor
therapeutic agents. Here, we develop a drug carrier through the attachment of substrate of …

Rationale: Tumor microenvironment interacts with tumor cells to regulate their stemness
properties through various cytokines and cytokine receptors. Previous studies revealed the …

Background Super enhancers (SE) play pivotal roles in cell identity and diseases occur
including tumorigenesis. The depletion of SE‐associated lncRNA transcripts, also known as …