The adaptive immune system has the important ability to generate and maintain a memory
for antigens once encountered. Recent progress in understanding the organization of …

Tissue-resident memory T cells (TRM) have recently emerged as crucial cellular players for
host defense in a wide variety of tissues and barrier sites. Insights into the maintenance and …

Tissue-resident lymphocytes provide organ-adapted protection against invading pathogens.
Whereas their biology has been examined in great detail in various infection models, their …

Circulating, blood-borne SARS-CoV-2-reactive memory T cells in persons so far unexposed
to SARS-CoV-2 or the vaccines have been described in 20-100% of the adult population …

The measles-mumps-rubella (MMR) vaccine has been widely used in the US, but measles
and mumps outbreaks remain a public health issue in the US and elsewhere, even among …

It has been 25 years since we first described long‐lived memory plasma cells of the bone
marrow, 13 years since we identified bone marrow resident memory T cells and 2 years …

Measles live attenuated vaccine (MV) induces strong humoral and cellular systemic memory
responses allowing the successful control of measles since decades. MV has also been …

The fact that T-cell numbers remain relatively stable throughout life, and that T-cell
proliferation rates increase during lymphopenia, has led to the consensus that T-cell …

Cytokine production by memory T cells is very important for T cell mediated protection.
Particularly multifunctional memory T cells that produce multiple cytokines have been …

Tissue resident memory T cells (TRM) have recently emerged as crucial cellular players for
host defense in a wide variety of tissues and barrier sites. Mouse models revealed that they …